PDB ID 7CCC     CHAIN C
Protein name F-actin-capping protein subunit alpha
Uniprot Accession Q5RKN9
The number of similar proteins 20
The number of binding states 6
The number of binding partners 7

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
7CCC (CHAIN: C)
1 P68135   P68135   Q923G3   Q12792  
2 P14315  
3 P14315   Q6EDY6  
4 P14315   Q6EDY6  
5 P14315   Q91YR1  
6 P14315   P58546  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MADFEDRVSD   EEKVRIAAKF   ITHAPPGEFN   EVFNDVRLLL   NNDNLLREGA   50
51   AHAFAQYNMD   QFTPVKIEGY   DDQVLITEHG   DLGNSRFLDP   RNQISFKFDH   100
101   LRKEASDPQP   EDVDGGLKSW   RESCDSALRA   YVKDHYSNGF   CTVYAKTIDG   150
151   QQTIIACIES   HQFQPKNFWN   GRWRSEWKFT   ITPPSAQVVG   VLKIQVHYYE   200
201   DGNVQLVSHK   DVQDSVTVSN   EVQTTKEFIK   IIESAENEYQ   TAISENYQTM   250
251   SDTTFKALRR   QLPVTRTKID   WNKILSYKIG   KEMQNA     300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
10_ASP ASN gnomAD
chr1:113162494
rs41283062
- 0.0122157 -
12_GLU LYS gnomAD
chr1:113162500
rs149653791
- 0.00192834 -
18_ALA THR gnomAD
chr7:116528193
rs201789411
- 0.000299664 -
44_ASN SER gnomAD
chr1:113192067
rs76726860
- 0.000286821 -
81_ASP ASN gnomAD
chr7:116544252
rs370326853
- 0.000497754 -
92_ASN LYS gnomAD
chr1:113197143
rs371346893
- 0.000406151 -
94_ILE MET gnomAD
chr7:116544293
rs144500777
- 0.000202893 -
112_GLU LYS gnomAD
chr1:113197201
rs201525157
- 0.000263145 -
135_HIS TYR gnomAD
chr1:113197270
rs201509858
- 0.000264247 -
154_ILE THR gnomAD
chr1:113201678
rs552715621
- 0.000139359 -
181_ILE VAL gnomAD
chr7:116550321
rs141641730
- 0.000417907 -
211_ASP GLU gnomAD
chr1:113209743
rs199731043
- 0.00013179 -
215_SER CYS gnomAD
chr7:116552181
rs140848019
- 0.000657334 -
226_LYS ARG gnomAD
chr1:113212184
rs147970114
- 0.000155925 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.