PDB ID 6J04     CHAIN A
Protein name Microtubule-associated proteins 1A/1B light chain 3B
Uniprot Accession Q9GZQ8
The number of similar proteins 40
The number of binding states 7
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
6J04 (CHAIN: A)
1 Monomeric state
2 Q9GZQ8  
3 Q5ZUV9  
4 Q9Y4P1  
5 Q9GZQ8   Q9GZQ8  
6 Q0PF16   Q0PF16  
7 Q9GZQ8   Q9GZQ8   Q9GZQ8  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   GPSEKTFKQR   RTFEQRVEDV   RLIREQHPTK   IPVIIERYKG   EKQLPVLDKT   50
51   KFLVPDHVNM   SELIKIIRRR   LQLNANQAFF   LLVNGHSMVS   VSTPISEVYE   100
101   SEKDEDGFLY   MVYASQETFM   KLSV       150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
14_GLU LYS gnomAD
chr12:117013787
rs192133007
- 0.000135191 -
20_VAL ILE 8.3kJPN
chr16:87432438
-
- 0.0001 -
22_LEU PHE 8.3kJPN
chr12:117013811
-
- 0.0001 -
25_GLU GLN gnomAD
chr16:87432453
rs113610787
- 0.0060481 -
27_HIS TYR 8.3kJPN
chr20:33147050
-
- 0.0001 -
32_PRO SER 8.3kJPN
chr12:117013841
-
- 0.0001 -
34_ILE MET 8.3kJPN
chr16:87435786
rs1158904097
- 0.0001 -
38_TYR HIS 8.3kJPN
chr12:117013859
rs200048902
- 0.0078 -
40_GLY SER 8.3kJPN
chr16:87435802
rs200880487
- 0.0001 -
43_GLN HIS 8.3kJPN
chr12:117013876
-
- 0.0001 -
46_VAL LEU 8.3kJPN
chr20:33147190
-
- 0.0001 -
50_THR SER gnomAD
chr20:33147203
rs755865335
- 0.000283569 -
60_MET LEU 8.3kJPN
chr12:117013925
-
- 0.0001 -
65_LYS GLU 8.3kJPN
chr16:87435877
rs760756783
- 0.0001 -
67_ILE SER 8.3kJPN
chr20:33147254
-
- 0.0001 -
68_ARG THR gnomAD
chr12:117013950
rs775368545
- 0.000111334 -
69_ARG LYS gnomAD
chr12:117013953
rs144234011
- 0.00322073 -
69_ARG GLY 8.3kJPN
chr20:33147541
-
- 0.0001 -
70_ARG CYS 8.3kJPN
chr12:117013955
-
- 0.0001 -
76_ASN HIS 8.3kJPN
chr16:87436551
rs1420825485
- 0.0004 -
85_GLY GLU 8.3kJPN
chr16:87436579
-
- 0.0001 -
91_VAL PHE 8.3kJPN
chr16:87436596
-
- 0.0001 -
107_GLY SER 8.3kJPN
chr20:33147655
rs1347928984
- 0.0001 -
112_VAL ILE 8.3kJPN
chr12:117014081
-
- 0.0001 -
113_CYS TYR gnomAD
chr12:117014085
rs111327250
- 0.0059828 -
113_TYR CYS gnomAD
chr16:87436663
rs200708875
- 0.00128707 -
117_GLU VAL gnomAD
chr12:117014097
rs142080200
- 0.00322113 -
118_THR ALA gnomAD
chr12:117014099
rs113585095
- 0.00611404 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.