PDB ID 4YFD     CHAIN A
Protein name Receptor-type tyrosine-protein phosphatase delta
Uniprot Accession Q64487
The number of similar proteins 6
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
4YFD (CHAIN: A)
1 Q61730  
2 Q64487  
3 Q810C0  
4 Q96NI6  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   ETPPRFTRTP   VDQTGVSGGV   ASFICQATGD   PRPKIVWNKK   GKKVSNQRFE   50
51   VIEFDDGSGS   VLRIQPLRTP   RDEAIYECVA   SNNVGEISVS   TRLTVLREDQ   100
101   IPRGFPTIDM   GPQLKVVERT   RTATMLCAAS   GNPDPEITWF   KDFLPVDTSN   150
151   NNGRIKQLRS   ESIGGTPIRG   ALQIEQSEES   DQGKYECVAT   NSAGTRYSAP   200
201   ANLYVRELRE   VRRVPPRFSI   PPTNHEIMPG   GSVNITCVAV   GSPMPYVKWM   250
251   LGAEDLTPED   DMPIGRNVLE   LNDVRQSANY   TCVAMSTLGV   IEAIAQITVK   300
301   ALPKPPGTPV   VTESTATSIT   LTWDSGNPEP   VSYYIIQHKP   KNSEEPYKEI   350
351   DGIATTRYSV   AGLSPYSDYE   FRVVAVNNIG   RGPASEPVLT   QTSEQAPSSA   400
401   PRDVQARMLS   STTILVQWKE   PEEPNGQIQG   YRVYYTMDPT   QHVNNWMKHN   450
451   VADSQITTIG   NLVPQKTYSV   KVLAFTSIGD   GPLSSDIQVI   T   500

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
44_SER PRO 4.7kJPN
chr9:8636800
-
- 0.0001 -
96_THR ILE 4.7kJPN
chr9:8633403
rs1208308933
- 0.0001 -
196_ARG LYS 4.7kJPN
chr9:8526629
-
- 0.0001 -
260_VAL ILE 4.7kJPN
chr9:8521481
rs760428875
- 0.0001 -
280_ALA VAL 4.7kJPN
chr9:8521420
rs746204840
- 0.0001 -
283_LEU VAL 4.7kJPN
chr9:8521412
-
- 0.0001 -
310_VAL ALA 4.7kJPN
chr9:8521330
rs188344530
- 0.0001 -
365_HIS TYR 4.7kJPN
chr9:8518319
rs762218066
- 0.0001 -
446_LYS ARG 4.7kJPN
chr9:8518075
-
- 0.0001 -
454_GLN GLU 4.7kJPN
chr9:8518052
rs10977171
- 0.1102 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.