PDB ID | 4QRS
|
CHAIN | B |
---|---|---|---|
Protein name | Beta-2-microglobulin | ||
Uniprot Accession | P61769 | ||
The number of similar proteins | 763 | ||
The number of binding states | 25 | ||
The number of binding partners | 16 |
Unicolor (beige)
The number of binding partners
Group
Binding state |
Binding partners |
---|---|
4QRS (CHAIN: B) | |
1 |
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2 | Monomeric state |
3 |
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4 |
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5 |
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6 |
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7 |
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8 |
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9 |
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10 |
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11 |
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12 |
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13 |
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14 |
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15 |
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16 |
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17 |
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18 |
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19 |
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20 |
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21 |
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22 |
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23 |
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24 |
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25 |
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Only interaction residues |
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|
Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
---|---|---|---|---|---|---|---|
33_SER | PRO |
8.3kJPN chr15:45007710 |
-
|
- | 0.0001 | - | |
44_GLU | ASP |
8.3kJPN chr15:45007745 |
-
|
- | 0.0001 | - | |
76_ASP | ASN | VAR_076691 |
rs398122820
|
Disease | - | Amyloidosis 8 (AMYL8) [MIM:105200] | |
76_ASP | ASN |
ClinVar chr15:45007839 |
rs398122820
|
Pathogenic | - | Familial visceral amyloidosis, Ostertag type [MedGen:C0268389,OMIM:105200,Orphanet:ORPHA85450,SNOMED CT:66451004] |