PDB ID 4NOJ     CHAIN A
Protein name Legumain
Uniprot Accession O89017
The number of similar proteins 15
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
4NOJ (CHAIN: A)
1 Monomeric state
2 Q99538  
3 Q15828  
4 B9V973  
5 Q3Y9I4  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   DGGKHWVVIV   AGSNGWYNYR   HQADACHAYQ   IIHRNGIPDE   QIIVMMYDDI   50
51   ANSEENPTPG   VVINRPNGTD   VYKGVLKDYT   GEDVTPENFL   AVLRGDAEAV   100
101   KGKGSGKVLK   SGPRDHVFIY   FTDHGATGIL   VFPNDDLHVK   DLNKTIRYMY   150
151   EHKMYQKMVF   YIEACESGSM   MNHLPDDINV   YATTAANPKE   SSYACYYDEE   200
201   RGTYLGDWYS   VNWMEDSDVE   DLTKETLHKQ   YHLVKSHTNT   SHVMQYGNKS   250
251   ISTMKVMQFQ   GMK         300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
51_ALA THR 8.3kJPN
chr14:93185183
rs1172792499
- 0.0001 -
69_VAL ILE gnomAD
chr14:93185129
rs118128989
- 0.00213964 -
69_VAL ILE 8.3kJPN
chr14:93185129
rs118128989
- 0.0112 -
70_VAL MET 8.3kJPN
chr14:93185126
-
- 0.0001 -
74_ASP ASN gnomAD
chr14:93185114
rs143384572
- 0.000103413 -
106_THR ALA gnomAD
chr14:93183733
rs760405421
- 0.000155219 -
122_ASP ASN 8.3kJPN
chr14:93182527
rs755309129
- 0.0001 -
132_GLY SER 8.3kJPN
chr14:93182497
rs369708299
- 0.0001 -
182_ARG TER 8.3kJPN
chr14:93180173
rs1316163364
- 0.0001 -
201_PRO LEU 8.3kJPN
chr14:93179164
rs767320292
- 0.0013 -
210_THR ILE 8.3kJPN
chr14:93178288
-
- 0.0001 -
213_ASN THR gnomAD
chr14:93178279
rs143914416
- 0.000334169 -
213_ASN SER 8.3kJPN
chr14:93178279
-
- 0.0001 -
229_THR MET 8.3kJPN
chr14:93178231
rs199988257
- 0.0001 -
237_VAL ILE 8.3kJPN
chr14:93178208
rs762575227
- 0.0001 -
275_LYS ARG 8.3kJPN
chr14:93178005
rs753385643
- 0.0003 -
277_ILE VAL 8.3kJPN
chr14:93176214
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.