PDB ID 4K71     CHAIN B
Protein name IgG receptor FcRn large subunit p51
Uniprot Accession P55899
The number of similar proteins 13
The number of binding states 6
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
4K71 (CHAIN: B)
1 P61769   P02768  
2 Monomeric state
3 P61769  
4 6FGB   6FGB   P61769  
5 5WHK   P61769   5WHK  
6 P61769   P01857   P02768  

Downdload

Format:

Molecule viewer

#binding
partners
  3
  2
  1
  0

Sequence information

1   AESHLSLLYH   LTAVSSPAPG   TPAFWVSGWL   GPQQYLSYNS   LRGEAEPCGA   50
51   WVWENQVSWY   WEKETTDLRI   KEKLFLEAFK   ALGGKGPYTL   QGLLGCELGP   100
101   DNTSVPTAKF   ALNGEEFMNF   DLKQGTWGGD   WPEALAISQR   WQQQDKAANK   150
151   ELTFLLFSCP   HRLREHLERG   RGNLEWKEPP   SMRLKARPSS   PGFSVLTCSA   200
201   FSFYPPELQL   RFLRNGLAAG   TGQGDFGPNS   DGSFHASSSL   TVKSGDEHHY   250
251   CCIVQHAGLA   QPLRVELESP   AKSS       300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
14_VAL GLY 4.7kJPN
chr19:50017175
-
- 0.0021 -
32_PRO LEU 4.7kJPN
chr19:50017229
rs764132164
- 0.0002 -
45_ALA VAL 4.7kJPN
chr19:50017268
rs756120751
- 0.0001 -
76_LEU VAL 4.7kJPN
chr19:50017360
-
- 0.0001 -
83_GLY ARG 4.7kJPN
chr19:50017381
rs201043787
- 0.0001 -
105_VAL LEU 4.7kJPN
chr19:50017524
-
- 0.0002 -
140_ARG LEU 4.7kJPN
chr19:50017630
-
- 0.0002 -
162_ARG HIS 4.7kJPN
chr19:50017696
rs200294618
- 0.0001 -
183_ARG CYS 4.7kJPN
chr19:50027778
rs779240739
- 0.0002 -
187_ARG GLN 4.7kJPN
chr19:50027791
rs747515242
- 0.0013 -
214_ARG GLN 4.7kJPN
chr19:50027872
rs147601685
- 0.0038 -
236_ALA THR 4.7kJPN
chr19:50027937
rs767515922
- 0.0001 -
246_ASP ASN 4.7kJPN
chr19:50027967
rs573657624
- 0.0002 -
258_GLY VAL 4.7kJPN
chr19:50028004
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.