PDB ID 4K71     CHAIN B
Protein name IgG receptor FcRn large subunit p51
Uniprot Accession P55899
The number of similar proteins 20
The number of binding states 7
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
4K71 (CHAIN: B)
1 P61769   P02768  
2 Monomeric state
3 P61769  
4 7Q15   P61769  
5 P61769   6FGB   6FGB  
6 P61769   5WHK   5WHK  
7 P01857   P61769   P02768  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   AESHLSLLYH   LTAVSSPAPG   TPAFWVSGWL   GPQQYLSYNS   LRGEAEPCGA   50
51   WVWENQVSWY   WEKETTDLRI   KEKLFLEAFK   ALGGKGPYTL   QGLLGCELGP   100
101   DNTSVPTAKF   ALNGEEFMNF   DLKQGTWGGD   WPEALAISQR   WQQQDKAANK   150
151   ELTFLLFSCP   HRLREHLERG   RGNLEWKEPP   SMRLKARPSS   PGFSVLTCSA   200
201   FSFYPPELQL   RFLRNGLAAG   TGQGDFGPNS   DGSFHASSSL   TVKSGDEHHY   250
251   CCIVQHAGLA   QPLRVELESP   AKSS       300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
14_VAL GLY 8.3kJPN
chr19:50017175
-
- 0.0033 -
20_GLY ARG gnomAD
chr19:50017192
rs548622027
- 0.000322671 -
32_PRO LEU 8.3kJPN
chr19:50017229
rs764132164
- 0.0004 -
42_ARG GLN gnomAD
chr19:50017259
rs566716525
- 0.000111776 -
45_ALA VAL 8.3kJPN
chr19:50017268
rs756120751
- 0.0001 -
48_CYS TYR gnomAD
chr19:50017277
rs151255924
- 0.000860069 -
68_LEU GLN 8.3kJPN
chr19:50017337
-
- 0.0001 -
76_LEU VAL 8.3kJPN
chr19:50017360
-
- 0.0001 -
83_GLY ARG 8.3kJPN
chr19:50017381
rs201043787
- 0.0001 -
105_VAL LEU 8.3kJPN
chr19:50017524
-
- 0.0001 -
109_LYS ASN gnomAD
chr19:50017538
rs150420714
- 0.0065323 -
140_ARG LEU 8.3kJPN
chr19:50017630
-
- 0.0002 -
160_PRO SER 8.3kJPN
chr19:50017689
rs373482955
- 0.0001 -
162_ARG HIS 8.3kJPN
chr19:50017696
rs200294618
- 0.0001 -
164_ARG TRP gnomAD
chr19:50017701
rs145251123
- 0.000189109 -
183_ARG CYS 8.3kJPN
chr19:50027778
rs779240739
- 0.0001 -
184_LEU VAL gnomAD
chr19:50027781
rs141886822
- 0.000196207 -
187_ARG GLN 8.3kJPN
chr19:50027791
rs747515242
- 0.001 -
214_ARG GLN 8.3kJPN
chr19:50027872
rs147601685
- 0.0037 -
236_ALA THR 8.3kJPN
chr19:50027937
rs767515922
- 0.0001 -
246_ASP ASN 8.3kJPN
chr19:50027967
rs573657624
- 0.0002 -
257_ALA VAL 8.3kJPN
chr19:50028001
rs777748221
- 0.0001 -
258_GLY VAL 8.3kJPN
chr19:50028004
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.