PDB ID 4GDK     CHAIN B
Protein name Autophagy protein 5
Uniprot Accession Q9H1Y0
The number of similar proteins 10
The number of binding states 6
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
4GDK (CHAIN: B)
1 Q676U5   Q676U5   O94817  
2 Q676U5  
3 Q7Z6L1  
4 Q676U5  
5 Q676U5   O94817  
6 Q676U5   Q676U5  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MTDDKDVLRD   VWFGRIPTCF   TLYQDEITER   EAEPYYLLLP   RVSYLTLVTD   50
51   KVKKHFQKVM   RQEDISEIWF   EYEGTPLKWH   YPIGLLFDLL   ASSSALPWNI   100
101   TVHFKSFPEK   DLLHCPSKDA   IEAHFMSCMK   EADALKHKSQ   VINEMQKKDH   150
151   KQLWMGLQND   RFDQFWAINR   KLMEYPAEEN   GFRYIPFRIY   QTTTERPFIQ   200
201   KLFRPVAADG   QLHTLGDLLK   EVCPSAIDPE   DGEKKNQVMI   HGIEPMLETP   250
251   LQWLSEHLSY   PDNFLHISII   PQPTD       300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
58_LYS MET VAR_036243 -
Unclassified - A colorectal cancer sample
65_ILE VAL 4.7kJPN
chr6:106756282
rs77859116
- 0.0465 -
83_ILE VAL 4.7kJPN
chr6:106740971
rs992870714
- 0.0002 -
93_SER ARG 4.7kJPN
chr6:106740939
-
- 0.0001 -
122_GLU ASP VAR_079274 rs1131692265
Disease - Spinocerebellar ataxia, autosomal recessive, 25 (SCAR25) [MIM:617584]
122_GLU ASP ClinVar
chr6:106727648
rs1131692265
Pathogenic - SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 25 [MedGen:C4539808,OMIM:617584]
141_VAL ILE 4.7kJPN
chr6:106727593
rs765419687
- 0.0006 -
167_ALA SER 4.7kJPN
chr6:106696099
rs376999465
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.