PDB ID 3ZNI     CHAIN C
Protein name UBIQUITIN-CONJUGATING ENZYME E2 D2
Uniprot Accession P62837
The number of similar proteins 68
The number of binding states 30
The number of binding partners 19

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   ALKRIHKELN   DLARDPPAQC   RAGPVGDDMF   HWQATIMGPN   DSPYQGGVFF   50
51   LTIHFPTDYP   FKPPKVAFTT   RIYHPNINSN   GSIKLDILRS   QWSPALTISK   100
101   VLLSICSLLC   DPNPDDPLVP   EIARIYKTDR   EKYNRIAREW   TQKYAM   150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
4_LYS ARG 8.3kJPN
chr4:103789885
rs763563358
- 0.0001 -
15_ARG TRP 8.3kJPN
chr5:138979975
-
- 0.0001 -
15_ARG CYS 8.3kJPN
chr10:60121116
rs769541649
- 0.0001 -
26_VAL LEU 8.3kJPN
chr7:43978081
-
- 0.0001 -
27_GLY SER gnomAD
chr7:43978084
rs61751727
- 0.0211142 -
29_ASP ASN 8.3kJPN
chr10:60121158
-
- 0.0001 -
34_GLN LYS gnomAD
chr10:60121266
rs201319430
- 0.00484562 -
38_MET THR gnomAD
chr7:43982449
rs545471592
- 0.000115332 -
73_ILE MET 8.3kJPN
chr7:43988251
rs752952683
- 0.0001 -
81_ASN SER 8.3kJPN
chr7:43988274
rs745714915
- 0.0001 -
140_GLU ASP 8.3kJPN
chr7:43992270
-
- 0.0001 -
146_ALA THR gnomAD
chr4:103720097
rs147920467
- 0.0016937 -
146_ALA SER 8.3kJPN
chr7:43992286
rs1417356646
- 0.0005 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.