PDB ID 3W97     CHAIN D
Protein name Histone H2B type 1-J
Uniprot Accession P06899
The number of similar proteins 178
The number of binding states 15
The number of binding partners 13

Molecule viewer

#binding
partners
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   GSHMDGKKRK   RSRKESYSIY   VYKVLKQVHP   DTGISSKAMG   IMNSFVNDIF   50
51   ERIAGEASRL   AHYNKRSTIT   SREIQTAVRL   LLPGELAKHA   VSEGTKAVTK   100
101   YTSAK           150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
32_THR ILE 4.7kJPN
chr6:25727237
rs147766950
- 0.0001 -
32_SER ARG 4.7kJPN
chr6:26184120
-
- 0.0001 -
35_GLU TER 4.7kJPN
chr6:25727245
-
- 0.0001 -
38_SER ALA 4.7kJPN
chr1:149858076
-
- 0.0001 -
38_SER CYS 4.7kJPN
chr6:26216756
-
- 0.0002 -
38_SER CYS 4.7kJPN
chr6:26251994
-
- 0.0003 -
39_VAL LEU 4.7kJPN
chr6:27775567
rs780283212
- 0.0001 -
44_VAL LEU 4.7kJPN
chr6:26252011
rs774570728
- 0.0003 -
50_PRO THR 4.7kJPN
chr6:27100379
rs774667736
- 0.0003 -
51_ASP ASN 4.7kJPN
chr6:26252032
-
- 0.0001 -
51_ASP GLY 4.7kJPN
chr6:27782976
-
- 0.0001 -
52_THR SER 4.7kJPN
chr6:26199944
-
- 0.0001 -
52_THR ALA 4.7kJPN
chr6:26273360
rs1458054891
- 0.0001 -
53_GLY ALA 4.7kJPN
chr6:26043725
-
- 0.0001 -
53_GLY SER 4.7kJPN
chr6:26199946
-
- 0.0001 -
53_GLY SER 4.7kJPN
chr6:27775525
-
- 0.0001 -
54_ILE VAL 4.7kJPN
chr6:26216709
-
- 0.0001 -
55_SER LEU 4.7kJPN
chr1:228645997
rs1353478558
- 0.0001 -
55_SER PHE 4.7kJPN
chr6:26252045
rs750512885
- 0.0001 -
56_SER PHE 4.7kJPN
chr6:26043716
-
- 0.0001 -
59_MET ILE 4.7kJPN
chr1:228646010
rs1440295879
- 0.0001 -
59_MET LEU 4.7kJPN
chr6:26252056
-
- 0.0001 -
60_GLY SER 4.7kJPN
chr6:27861421
rs1410298024
- 0.0001 -
62_MET ILE 4.7kJPN
chr6:27100341
rs1402019530
- 0.0001 -
63_ASN SER 4.7kJPN
chr6:25727330
rs1237711095
- 0.0001 -
66_VAL ILE 4.7kJPN
chr1:149783680
rs1438376476
- 0.0002 -
69_ILE VAL 4.7kJPN
chr1:228646038
rs779849447
- 0.0001 -
70_PHE SER 4.7kJPN
chr6:25727351
rs1431133085
- 0.0001 -
72_ARG CYS 4.7kJPN
chr6:26273420
rs757772183
- 0.0001 -
72_ARG CYS 4.7kJPN
chr6:27861457
-
- 0.0001 -
73_ILE LEU 4.7kJPN
chr6:25727359
-
- 0.0001 -
75_SER GLY 4.7kJPN
chr6:27775459
rs1264351950
- 0.0001 -
77_ALA SER 4.7kJPN
chr1:149857959
-
- 0.0003 -
77_ALA VAL 4.7kJPN
chr1:228646063
rs759631368
- 0.0002 -
78_SER PRO 4.7kJPN
chr1:228646065
-
- 0.0001 -
79_ARG LEU 4.7kJPN
chr1:228646069
rs1244127669
- 0.0001 -
81_ALA GLU 4.7kJPN
chr6:26123888
rs752759673
- 0.0001 -
81_ALA THR 4.7kJPN
chr6:26216628
-
- 0.0001 -
81_ALA THR 4.7kJPN
chr6:26252122
rs745564288
- 0.0021 -
84_ASN SER 4.7kJPN
chr6:26252132
rs542798893
- 0.0003 -
87_SER TER 4.7kJPN
chr6:26184286
rs191131837
- 0.0029 -
92_ARG GLY 4.7kJPN
chr6:26184300
-
- 0.0001 -
92_ARG LYS 4.7kJPN
chr6:26273481
-
- 0.0001 -
93_GLU TER 4.7kJPN
chr6:26158677
-
- 0.0001 -
94_ILE PHE 4.7kJPN
chr6:27806722
-
- 0.0002 -
97_ALA THR 4.7kJPN
chr6:26043594
-
- 0.0001 -
101_LEU MET 4.7kJPN
chr6:26043582
-
- 0.0002 -
107_ALA SER 4.7kJPN
chr6:27114256
-
- 0.0001 -
110_ALA THR 4.7kJPN
chr6:27775354
-
- 0.0001 -
122_THR SER 4.7kJPN
chr6:26043518
rs1266161609
- 0.0001 -
124_SER PHE 4.7kJPN
chr6:25727513
rs201800096
- 0.0005 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.