PDB ID 3RK2     CHAIN C
Protein name Synaptosomal-associated protein 25
Uniprot Accession P60880
The number of similar proteins 23
The number of binding states 8
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   GSHMMRNELE   EMQRRADQLA   DESLESTRRM   LQLVEESKDA   GIRTLVMLDE   50
51   QGEQLDRVEE   GMNHINQDMK   EAEKNLKDLG   W     100

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
48_VAL PHE ClinVar
chr20:10265399
rs797044873
Likely pathogenic - Inborn genetic diseases [MeSH:D030342,MedGen:C0950123]
67_ILE ASN VAR_073698 -
Disease - Myasthenic syndrome, congenital, 18 (CMS18) [MIM:616330]
67_ILE ASN ClinVar
chr20:10273845
rs1555794286
Pathogenic - Myasthenic syndrome, congenital, 18 [MedGen:C4225364,OMIM:616330]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.