PDB ID 3KWQ     CHAIN B
Protein name Histone H4
Uniprot Accession P62799
The number of similar proteins 228
The number of binding states 22
The number of binding partners 19

Molecule viewer

#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   KVLRDNIQGI   TKPAIRRLAR   RGGVKRISGL   IYEETRGVLK   VFLENVIRDA   50
51   VTYTEHAKRK   TVTAMDVVYA   LKRQGRTLYG   FGG     100

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
31_LYS GLN 4.7kJPN
chr6:26027387
-
- 0.0001 -
33_ALA VAL 4.7kJPN
chr6:26022007
rs776166186
- 0.0001 -
33_ALA THR 4.7kJPN
chr6:26027381
-
- 0.0001 -
37_LEU PHE 4.7kJPN
chr6:27107199
-
- 0.0001 -
45_ARG TER 4.7kJPN
chr6:26027345
rs767025164
- 0.0001 -
47_SER TER 4.7kJPN
chr6:26240796
-
- 0.0001 -
52_GLU ALA 4.7kJPN
chr6:26027323
-
- 0.0001 -
55_ARG HIS 4.7kJPN
chr6:26027314
rs1195708639
- 0.0003 -
55_ARG TRP 4.7kJPN
chr12:14923853
rs762150713
- 0.0001 -
57_VAL LEU 4.7kJPN
chr6:26189133
-
- 0.0001 -
57_VAL LEU 4.7kJPN
chr6:26247034
rs200377159
- 0.0086 -
57_VAL MET 4.7kJPN
chr6:27107259
rs1013949364
- 0.0001 -
60_VAL ALA 4.7kJPN
chr6:26027299
rs780045847
- 0.0002 -
61_PHE LEU 4.7kJPN
chr6:27799120
rs746877857
- 0.0002 -
64_ASN ASP 4.7kJPN
chr6:26240846
-
- 0.0001 -
65_VAL ILE 4.7kJPN
chr6:26104371
-
- 0.0001 -
67_ARG TRP 4.7kJPN
chr6:27107289
rs1291040170
- 0.0005 -
70_VAL MET 4.7kJPN
chr6:26246995
rs140916075
- 0.0001 -
73_THR PRO 4.7kJPN
chr12:14923799
rs1171400276
- 0.0003 -
78_ARG SER 4.7kJPN
chr6:26022141
-
- 0.0001 -
78_ARG SER 4.7kJPN
chr6:27107322
-
- 0.0001 -
82_THR ILE 4.7kJPN
chr6:26189057
rs144742137
- 0.0048 -
82_THR ILE 4.7kJPN
chr6:27799058
rs372460457
- 0.0001 -
84_MET ILE 4.7kJPN
chr6:27792157
-
- 0.0004 -
85_ASP ASN 4.7kJPN
chr6:26240909
-
- 0.0003 -
88_TYR HIS 4.7kJPN
chr12:14923754
-
- 0.0001 -
89_ALA THR 4.7kJPN
chr6:26104443
rs144469714
- 0.0001 -
89_ALA VAL 4.7kJPN
chr6:26104444
-
- 0.0001 -
89_ALA THR 4.7kJPN
chr12:14923751
rs776707867
- 0.0001 -
90_LEU PRO 4.7kJPN
chr6:26205144
-
- 0.0001 -
92_ARG SER 4.7kJPN
chr6:26022183
-
- 0.0001 -
92_ARG CYS 4.7kJPN
chr6:26104452
-
- 0.0001 -
92_ARG SER 4.7kJPN
chr6:27107364
-
- 0.0001 -
99_GLY VAL 4.7kJPN
chr6:26027182
-
- 0.0001 -
99_GLY ASP 4.7kJPN
chr6:27840990
-
- 0.0001 -
102_GLY ASP 4.7kJPN
chr6:26240961
rs151068394
- 0.0074 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.