PDB ID 3JUA     CHAIN A
Protein name Transcriptional enhancer factor TEF-3
Uniprot Accession Q62296
The number of similar proteins 17
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
3JUA (CHAIN: A)
1 P46938  
2 Q62296  
3 Q99NC0  
4 Q80V24  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   SMRSIASSKL   WMLEFSAFLE   RQQDPDTYNK   HLFVHISQSS   PSYSDPYLET   50
51   VDIRQIYDKF   PEKKGGLKEL   FERGPSNAFF   LVKFWADLNT   NIDDEGSAFY   100
101   GVSSQYESPE   NMIITCSTKV   CSFGKQVVEK   VETEYARYEN   GHYLYRIHRS   150
151   PLCEYMINFI   HKLKHLPEKY   MMNSVLENFT   ILQVVTNRDT   QETLLCIAYV   200
201   FEVSASEHGA   QHHIYRLVKE         250

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
218_ARG HIS 4.7kJPN
chr11:12904623
rs188077520
- 0.012 -
232_PRO LEU 4.7kJPN
chr12:3129932
rs71583736
- 0.0004 -
234_SER LEU 4.7kJPN
chr11:12904671
rs140310944
- 0.0001 -
237_LYS GLU 4.7kJPN
chr12:3131016
-
- 0.0001 -
256_GLU LYS 4.7kJPN
chr12:3131073
rs762656664
- 0.0002 -
261_ARG SER 4.7kJPN
chr12:3131088
-
- 0.0001 -
264_TYR CYS 4.7kJPN
chr12:3131098
rs765302453
- 0.0001 -
272_GLY SER 4.7kJPN
chr12:3131121
-
- 0.0001 -
281_GLY CYS 4.7kJPN
chr11:12923625
-
- 0.0001 -
284_ASN ASP 4.7kJPN
chr12:3131157
-
- 0.0001 -
289_VAL ILE 4.7kJPN
chr11:12923649
rs1243570522
- 0.0001 -
316_PRO SER 4.7kJPN
chr12:3147203
rs11550887
- 0.0006 -
317_GLU LYS 4.7kJPN
chr12:3147206
rs987014448
- 0.0001 -
320_ILE THR 4.7kJPN
chr12:3147216
-
- 0.0001 -
353_ARG HIS 4.7kJPN
chr12:3149313
rs1172939530
- 0.0002 -
356_ARG GLN 4.7kJPN
chr12:3149322
rs1326238086
- 0.0001 -
359_MET VAL 4.7kJPN
chr11:12951778
rs764902614
- 0.0001 -
384_GLU GLY 4.7kJPN
chr11:12951854
-
- 0.0001 -
398_GLN ARG 4.7kJPN
chr12:3149553
rs1279803067
- 0.0001 -
422_TYR HIS ClinVar
chr11:12958749
rs11567847
Pathogenic - Sveinsson chorioretinal atrophy [MedGen:C1862382,OMIM:108985,Orphanet:ORPHA86813]
(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.