PDB ID 3IHR     CHAIN A
Protein name Ubiquitin carboxyl-terminal hydrolase isozyme L5
Uniprot Accession Q9Y5K5
The number of similar proteins 8
The number of binding states 5
The number of binding partners 3

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3IHR (CHAIN: A)
1 Monomeric state
2 Q16186  
3 Q6P4R8  
4 Q6P4R8   P0CG47  
5 P0CG47   Q16186  

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Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   TGNAGEWCLX   ESDPGVFTEL   IKGFGCRGAQ   VEEIWSLEPE   NFEKLKPVHG   50
51   LIFLFKWQPG   EEPAGSVVQD   SRLDTIFFAK   QVINNACATQ   AIVSVLLNCT   100
101   HQDVHLGETL   SEFKEFSQSF   DAAXKGLALS   NSDVIRQVHN   SFARQQXFEF   150
151   DTKTSAKEED   AFHFVSYVPV   NGRLYELDGL   REGPIDLGAC   NQDDWISAVR   200
201   PVIEKRIQKY   SEGEIRFNLX   AIVSDRKXIY   EQKIAELQRQ   LAEEPXDTDQ   250
251   GNSXLSAIQS   EVAKNQXLIE   EEVQKLKRYK   IENIRRKHNY   LPFIXELLKT   300
301   LAEHQQLIPL   VEKAKEKQNA   KKAQETKS       350

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
78_PHE TYR gnomAD
chr1:193018889 		rs140990934
- 0.000264867 -
139_VAL ILE 8.3kJPN
chr1:192998537 		rs1434286375
- 0.0001 -
169_VAL LEU gnomAD
chr1:192998369 		rs139595729
- 0.000135478 -
192_ASN SER 8.3kJPN
chr1:192997269 		rs140645938
- 0.0001 -
197_ILE PHE VAR_011613 -
LB/B - -
209_GLN ARG 8.3kJPN
chr1:192997218 		-
- 0.0001 -
211_TYR HIS 8.3kJPN
chr1:192993075 		-
- 0.0002 -
240_ARG LYS 8.3kJPN
chr1:192992987 		-
- 0.0001 -
284_ASN SER 8.3kJPN
chr1:192990318 		rs1378466262
- 0.0003 -
297_GLU VAL 8.3kJPN
chr1:192990279 		rs1226750299
- 0.0001 -
310_PRO LEU 8.3kJPN
chr1:192990240 		-
- 0.0006 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.