PDB ID 3C8X     CHAIN A
Protein name Ephrin type-A receptor 2
Uniprot Accession P29317
The number of similar proteins 9
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3C8X (CHAIN: A)
1 P29317  
2 Monomeric state
3 P20827  
4 3SKJ   3SKJ  
5 P29317   P29317  

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Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   APEHHHHHHD   YDIPTTENLY   FQGAMDAAQG   KEVVLLDFAA   AGGELGWLTH   50
51   PYGKGWDLMQ   NIMNDMPIYM   YSVCNVMSGD   QDNWLRTNWV   YRGEAERIFI   100
101   ELKFTVRDCN   SFPGGASSCK   ETFNLYYAES   DLDYGTNFQK   RLFTKIDTIA   150
151   PDEITVSSDF   EARHVKLNVE   ERSVGPLTRK   GFYLAFQDIG   ACVALLSVRV   200
201   YYKKCP           250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
41_LEU VAL gnomAD
chr1:16477423 		rs147977279
- 0.00201257 -
93_ARG CYS gnomAD
chr1:16475419 		rs200152244
- 0.000350026 -
99_LYS ASN VAR_055989 rs1058372
Polymorphism - -
104_ASP GLY 8.3kJPN
chr1:16475385 		-
- 0.0001 -
104_ASP TYR 8.3kJPN
chr1:16475386 		-
- 0.0001 -
165_VAL MET gnomAD
chr1:16475203 		rs150790360
- 0.00137229 -
165_VAL MET 8.3kJPN
chr1:16475203 		rs150790360
- 0.0001 -
172_PRO LEU gnomAD
chr1:16475181 		rs751025996
- 0.000156264 -
175_ARG CYS gnomAD
chr1:16475173 		rs147352564
- 0.000385415 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.