PDB ID 2LZG     CHAIN A
Protein name E3 ubiquitin-protein ligase Mdm2
Uniprot Accession Q00987
The number of similar proteins 30
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2LZG (CHAIN: A)
1 Monomeric state
2 Q00987  
3 5WTS  
4 2M86  
5 Q00987   5SWK  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MCNTNMSVPT   DGAVTTSQIP   ASEQETLVRP   KPLLLKLLKS   VGAQKDTYTM   50
51   KEVLFYLGQY   IMTKRLYDEK   QQHIVYCSND   LLGDLFGVPS   FSVKEHRKIY   100
101   TMIYRNLVVV   NQQESSDSGT   SVSEN       150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
10_THR ILE 4.7kJPN
chr12:69203020
-
- 0.0001 -
38_LEU VAL 4.7kJPN
chr12:69207364
-
- 0.0001 -
120_THR ILE 4.7kJPN
chr12:69218161
rs1320937462
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.