PDB ID | 2F9L | CHAIN | A |
---|---|---|---|
Protein name | RAB11B, member RAS oncogene family | ||
Uniprot Accession | Q15907 | ||
The number of similar proteins | 35 | ||
The number of binding states | 12 | ||
The number of binding partners | 8 |
Unicolor (beige)
The number of binding partners
Group
Binding state |
Binding partners |
---|---|
2F9L (CHAIN: A) | |
1 | Monomeric state |
2 | Q64595 |
3 | Q9UBF8 |
4 | O60239 |
5 | Q96QF0 |
6 | Q9ULV0 |
7 | P62491 |
8 | O75154 |
9 | O75154 |
10 | O75154 Q96QF0 |
11 | Q7L804 Q7L804 |
12 | O75154 O75154 Q96QF0 |
Only interaction residues |
|
||||||||||||||||||||
|
Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
---|---|---|---|---|---|---|---|
22_VAL | MET | VAR_080598 |
rs1555690779
|
LP/P | - | Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter (NDAGSCW) [MIM:617807] | |
22_VAL | MET |
ClinVar chr19:8464770 |
rs1555690779
|
Pathogenic/Likely pathogenic | - | Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter [MONDO:MONDO:0060624,MedGen:C4540498,OMIM:617807] | |
68_ALA | THR | VAR_080599 |
rs1555690804
|
LP/P | - | Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter (NDAGSCW) [MIM:617807] | |
68_ALA | THR |
ClinVar chr19:8464908 |
rs1555690804
|
Pathogenic/Likely pathogenic | - | Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter|not provided [MONDO:MONDO:0060624,MedGen:C4540498,OMIM:617807|MedGen:C3661900] | |
102_VAL | MET |
8.3kJPN chr19:8467037 |
rs1437902263
|
- | 0.0001 | - | |
110_ARG | TRP |
8.3kJPN chr19:8467061 |
rs776189936
|
- | 0.0013 | - | |
112_HIS | ARG |
ClinVar chr15:66170198 |
-
|
Likely pathogenic | - | 7 conditions [7 conditions] | |
120_MET | VAL |
8.3kJPN chr15:66170221 |
-
|
- | 0.0001 | - | |
120_MET | ILE |
8.3kJPN chr19:8467093 |
-
|
- | 0.0001 | - | |
154_SER | LEU |
ClinVar chr15:66172039 |
-
|
Pathogenic/Likely pathogenic | - | not provided [MedGen:C3661900] |