PDB ID 2F9L     CHAIN A
Protein name RAB11B, member RAS oncogene family
Uniprot Accession Q15907
The number of similar proteins 33
The number of binding states 12
The number of binding partners 8

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2F9L (CHAIN: A)
1 Monomeric state
2 Q64595  
3 Q9UBF8  
4 O60239  
5 Q96QF0  
6 Q9ULV0  
7 P62491  
8 Q7L804  
9 O75154  
10 O75154   Q96QF0  
11 O75154   O75154  
12 O75154   O75154   Q96QF0  

Downdload

Format:

Molecule viewer

#binding
partners
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MYDYLFKVVL   IGDSGVGKSN   LLSRFTRNEF   NLESKSTIGV   EFATRSIQVD   50
51   GKTIKAQIWD   TAGQERYRRI   TSAYYRGAVG   ALLVYDIAKH   LTYENVERWL   100
101   KELRDHADSN   IVIMLVGNKS   DLRHLRAVPT   DEARAFAEKN   NLSFIETSAL   150
151   DSTNVEEAFK   NILTEIYRIV   SQKQIADRAA   HDESPGNNVV   DISVPPTTD   200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(4.7kJPN)		 Disease name
22_VAL MET VAR_080598 -
Disease - Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter (NDAGSCW) [MIM:617807]
22_VAL MET ClinVar
chr19:8464770 		rs1555690779
Pathogenic - NEURODEVELOPMENTAL DISORDER WITH ATAXIC GAIT, ABSENT SPEECH, AND DECREASED CORTICAL WHITE MATTER [MedGen:C4540498,OMIM:617807]
68_ALA THR VAR_080599 -
Disease - Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter (NDAGSCW) [MIM:617807]
68_ALA THR ClinVar
chr19:8464908 		rs1555690804
Pathogenic - NEURODEVELOPMENTAL DISORDER WITH ATAXIC GAIT, ABSENT SPEECH, AND DECREASED CORTICAL WHITE MATTER [MedGen:C4540498,OMIM:617807]
102_VAL MET 4.7kJPN
chr19:8467037 		rs1437902263
- 0.0001 -
115_SER ASN 4.7kJPN
chr19:8467077 		rs375511185
- 0.0001 -
120_MET VAL 4.7kJPN
chr15:66170221 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.