PDB ID 1Z8J     CHAIN A
Protein name Thrombin light chain
Uniprot Accession P00734
The number of similar proteins 294
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1Z8J (CHAIN: A)
1 P00734  
2 Monomeric state
3 P00734   P01008  
4 P00734   P00734  
5 P00734   P00734  
6 P00734   P00734   P00734  
7 P00734   P00734   P00734  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   TFFNPRTFGS   GEADCGLRPL   FEKKSLEDKT   ERELLESYID     50

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
1E_SER LEU 8.3kJPN
chr11:46748165 		rs200812621
- 0.0004 -
8_GLU LYS ClinVar
chr11:46748284 		rs121918483
Pathogenic - Hereditary factor II deficiency disease [MedGen:C0272317,SNOMED CT:33297000]
14C_GLU LYS ClinVar
chr11:46748311 		rs121918484
Pathogenic - Hereditary factor II deficiency disease [MedGen:C0272317,SNOMED CT:33297000]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.