PDB ID 1Z5S     CHAIN C
Protein name Ran GTPase-activating protein 1
Uniprot Accession P46060
The number of similar proteins 13
The number of binding states 3
The number of binding partners 3

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1Z5S (CHAIN: C)
1 P63165   P63279  
2 P63279  
3 P61956   Q9HC62  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   SLNTGEPAPV   LSSPPPADVS   TFLAFPSPEK   LLRLGPKSSV   LIAQQTDTSD   50
51   PEKVVSAFLK   VSSVFKDEAT   VRMAVQDAVD   ALMQKAFNSS   SFNSNTFLTR   100
101   LLVHMGLLKS   EDKVKAIANL   YGPLMALNHM   VQQDYFPKAL   APLLLAFVTK   150
151   PNSALESCSF   ARHSLLQTLY   KV       200

Variants

Residue AA Source /
dbSNP
Clinical
Significance
Allele
Frequency
(> 0.0001)
AlphaMissense
pathogenicity
Disease name
435_SER ALA 8.3kJPN
chr22:41648953
rs763423763
- 0.0001 0.0599 -
448_ARG HIS 8.3kJPN
chr22:41648913
rs1248671879
- 0.0001 0.1199 -
463_THR MET 8.3kJPN
chr22:41647106
rs761024189
- 0.0007 0.0903 -
506_SER PHE 8.3kJPN
chr22:41645788
rs750187143
- 0.0001 0.1102 -
561_ALA VAL 8.3kJPN
chr22:41645346
rs748108526
- 0.0001 0.2403 -
576_ALA PRO gnomAD
chr22:41642645
rs759935934
- 0.000144016 0.5204 -
583_THR MET 8.3kJPN
chr22:41642623
rs149544782
- 0.0001 0.1643 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.