PDB ID 1Z5S     CHAIN C
Protein name Ran GTPase-activating protein 1
Uniprot Accession P46060
The number of similar proteins 13
The number of binding states 3
The number of binding partners 3

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1Z5S (CHAIN: C)
1 P63165   P63279  
2 P63279  
3 P61956   Q9HC62  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   SLNTGEPAPV   LSSPPPADVS   TFLAFPSPEK   LLRLGPKSSV   LIAQQTDTSD   50
51   PEKVVSAFLK   VSSVFKDEAT   VRMAVQDAVD   ALMQKAFNSS   SFNSNTFLTR   100
101   LLVHMGLLKS   EDKVKAIANL   YGPLMALNHM   VQQDYFPKAL   APLLLAFVTK   150
151   PNSALESCSF   ARHSLLQTLY   KV       200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
435_SER ALA 8.3kJPN
chr22:41648953 		rs763423763
- 0.0001 -
448_ARG HIS 8.3kJPN
chr22:41648913 		rs1248671879
- 0.0001 -
463_THR MET 8.3kJPN
chr22:41647106 		rs761024189
- 0.0007 -
506_SER PHE 8.3kJPN
chr22:41645788 		rs750187143
- 0.0001 -
561_ALA VAL 8.3kJPN
chr22:41645346 		rs748108526
- 0.0001 -
576_ALA PRO gnomAD
chr22:41642645 		rs759935934
- 0.000144016 -
583_THR MET 8.3kJPN
chr22:41642623 		rs149544782
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.