PDB ID 1IZN     CHAIN A
Protein name CapZ alpha-1 subunit
Uniprot Accession P13127
The number of similar proteins 12
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1IZN (CHAIN: A)
1 P14315  
2 P14315   Q6EDY6  
3 P14315   Q6EDY6  
4 P14315   P62774  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MADFEDRVSD   EEKVRIAAKF   ITHAPPGEFN   EVFNDVRLLL   NNDNLLREGA   50
51   AHAFAQYNMD   QFTPVKIEGY   DDQVLITEHG   DLGNGRFLDP   RNKISFKFDH   100
101   LRKEASDPQP   EDTESALKQW   RDACDSALRA   YVKDHYPNGF   CTVYGKSIDG   150
151   QQTIIACIES   HQFQPKNFWN   GRWRSEWKFT   ITPPTAQVAA   VLKIQVHYYE   200
201   DGNVQLVSHK   DIQDSVQVSS   DVQTAKEFIK   IIENAENEYQ   TAISENYQTM   250
251   SDTTFKALRR   QLPVTRTKID   WNKILSYKIG   KEMQNA     300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
18_ALA VAL 4.7kJPN
chr7:116528194
-
- 0.0001 -
23_HIS ARG 4.7kJPN
chr7:116528209
-
- 0.0001 -
34_ASN SER 4.7kJPN
chr1:113189893
rs202216073
- 0.0001 -
36_VAL PHE 4.7kJPN
chr1:113192042
rs753793163
- 0.0001 -
44_ASN SER 4.7kJPN
chr1:113192067
rs76726860
- 0.0092 -
60_ASP ASN 4.7kJPN
chr1:113196242
rs776501930
- 0.0002 -
90_PRO SER 4.7kJPN
chr1:113197135
-
- 0.0001 -
100_HIS GLN 4.7kJPN
chr7:116544311
-
- 0.0002 -
103_LYS GLU 4.7kJPN
chr7:116544318
-
- 0.0001 -
148_ILE THR 4.7kJPN
chr1:113201660
-
- 0.0003 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.