PDB ID 1HYR     CHAIN A
Protein name NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN
Uniprot Accession P26718
The number of similar proteins 9
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1HYR (CHAIN: A)
1 P26718   Q9TQ92  
2 P26718  
3 P26718   Q5VY80  
4 P26718   Q8QN43  

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Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   NSLFNQEVQI   PLTESYCGPC   PKNWICYKNN   CYQFFDESKN   WYESQASCMS   50
51   QNASLLKVYS   KEDQDLLKLV   KSYHWMGLVH   IPTNGSWQWE   DGSILSPNLL   100
101   TIIEMQKGDC   ALYASSFKGY   IENCSTPNTY   ICMQRTV     150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
93_GLU LYS 8.3kJPN
chr12:10532046
rs774643686
- 0.0001 -
95_TYR ASP 8.3kJPN
chr12:10531299
-
- 0.0001 -
123_SER ASN 8.3kJPN
chr12:10531214
rs1408677482
- 0.0002 -
125_ALA SER gnomAD
chr12:10531209
rs147568901
- 0.000643532 -
125_ALA ASP 8.3kJPN
chr12:10531208
-
- 0.0001 -
177_ASN SER VAR_030738 rs2306182
Polymorphism - -
177_ASN SER gnomAD
chr12:10530734
rs2306182
- 0.000139326 -
177_ASN SER 8.3kJPN
chr12:10530734
rs2306182
- 0.0183 -
180_THR ALA 8.3kJPN
chr12:10525826
-
- 0.0006 -
205_THR ALA 8.3kJPN
chr12:10525751
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.