PDB ID 1H2T     CHAIN C
Protein name 80 KDA NUCLEAR CAP BINDING PROTEIN
Uniprot Accession Q09161
The number of similar proteins 11
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1H2T (CHAIN: C)
1 P52298  
2 P52298   P52292  
3 P52298   Q9BXP5  
4 P52298   Q86YN6  

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Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   KTSDANETED   HLESLICKVG   EKSACSLESN   LEGLAGVLEA   DLPNYKSKIL   50
51   RLLCTVARLL   PEKLTIYTTL   VGLLNARNYN   FGGEFVEAMI   RQLKESLKAN   100
101   NYNEAVYLVR   FLSDLVNCHV   IAAPSMVAMF   ENFVSVTQEE   DVPQVRRDWY   150
151   VYAFLSSLPW   VGKELYEKKD   AEMDRIFANT   ESYLKRRQKT   HVPMLQVWTA   200
201   DKPHPQEEYL   DCLWAQIQKL   KKDRWQERHI   LRPYLAFDSI   LCEALQHNLP   250
251   PFTPPPHTED   SVYPMPRVIF   RMFDYTDDPE   GPVMPGSHSV   ERFVIEENLH   300
301   CIIKSHWKER   KTCAAQLVSY   PGKNKIPLNY   HIVEVIFAEL   FQLPAPPHID   350
351   VMYTTLLIEL   CKLQPGSLPQ   VLAQATEMLY   MRLDTMNTTC   VDRFINWFSH   400
401   HLSNFQFRWS   WEDWSDCLSQ   DPESPKPKFV   REVLEKCMRL   SYHQRILDIV   450
451   PPTFSALCPS   NPTCIYKYGD   ESSNSLPGHS   VALCLAVAFK   SKATNDEIFS   500
501   ILKDVPNPNQ   DDDDDEGFSF   NPLKIEVFVQ   TLLHLAAKSF   SHSFSALAKF   550
551   HEVFKTLAES   DEGKLHVLRV   MFEVWRNHPQ   MIAVLVDKMI   RTQIVDCAAV   600
601   ANWIFSSELS   RDFTRLFVWE   ILHSTIRKMN   KHVGAQSEQK   NLFLVIFQRF   650
651   IMILTEHLVR   CETDGTSVLT   PWYKNCIERL   QQIFLQHHQI   IQQYMVTLEN   700
701   LLFTAELDPH   ILAVFQQFCA   LQA       750

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
64_TYR HIS 4.7kJPN
chr9:100403910
-
- 0.0001 -
213_MET THR 4.7kJPN
chr9:100409800
-
- 0.0001 -
259_ILE VAL 4.7kJPN
chr9:100410383
-
- 0.0001 -
275_PRO THR 4.7kJPN
chr9:100410431
-
- 0.0001 -
276_HIS ASP 4.7kJPN
chr9:100410434
-
- 0.0001 -
280_SER PRO 4.7kJPN
chr9:100410446
-
- 0.0001 -
290_ARG SER 4.7kJPN
chr9:100410478
-
- 0.0001 -
401_ARG CYS 4.7kJPN
chr9:100417192
-
- 0.0001 -
407_THR ALA 4.7kJPN
chr9:100417210
-
- 0.0001 -
450_ARG LYS 4.7kJPN
chr9:100418343
-
- 0.0002 -
454_GLU ASP 4.7kJPN
chr9:100418356
-
- 0.0001 -
596_ASN LYS 4.7kJPN
chr9:100425320
rs200307901
- 0.0016 -
646_ARG CYS 4.7kJPN
chr9:100429079
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.