PDB ID 1GZR     CHAIN B
Protein name INSULIN-LIKE GROWTH FACTOR I
Uniprot Accession P01343
The number of similar proteins 14
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1GZR (CHAIN: B)
1 Monomeric state
2 P22692  
3 P06213  
4 Q09024  
5 P08833   P22692  
6 P08069   P08069  
7 P01343   P01343   P24593   P24593  

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#binding
partners
  3
  2
  1
  0

Sequence information

1   GPETLCGAEL   VDALQFVCGD   RGFYFNKPTG   YGSSSRRAPQ   TGIVDECCFR   50
51   SCDLRRLEMY   CAPLKPAKSA         100

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(4.7kJPN)		 Disease name
19_GLY GLU 4.7kJPN
chr12:102869441 		-
- 0.0001 -
28_PRO HIS 4.7kJPN
chr12:102813462 		-
- 0.0001 -
44_VAL MET ClinVar
chr12:102813415 		rs121912430
Pathogenic - Insulin-like growth factor I deficiency [MedGen:C1837475,OMIM:608747,Orphanet:ORPHA73272]
50_ARG TRP ClinVar
chr12:102813397 		rs587779350
Pathogenic - Insulin-like growth factor I deficiency [MedGen:C1837475,OMIM:608747,Orphanet:ORPHA73272]
63_PRO THR 4.7kJPN
chr12:102813358 		-
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.