PDB ID 1G0X     CHAIN A
Protein name LEUCOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR-1
Uniprot Accession Q8NHL6
The number of similar proteins 11
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1G0X (CHAIN: A)
1 Monomeric state
2 Q8NHL6  
3 P61769   P01892  
4 P61769   Q4A1U8  

Downdload

Format:

Molecule viewer

#binding
partners
  2
  1
  0

Sequence information

1   HLPKPTLWAE   PGSVITQGSP   VTLRCQGGQE   TQEYRLYREK   KTAPWITRIP   50
51   QELVKKGQFP   IPSITWEHAG   RYRCYYGSDT   AGRSESSDPL   ELVVTGAYIK   100
101   PTLSAQPSPV   VNSGGNVTLQ   CDSQVAFDGF   ILCKEGEDEH   PQCLNSQPHA   150
151   RGSSRAIFSV   GPVSPSRRWW   YRCYAYDSNS   PYEWSLPSDL   LELLVLG   200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
3_LEU ILE 4.7kJPN
chr19:54803748
rs139099303
- 0.4055 -
17_THR ILE 4.7kJPN
chr19:54783882
rs75728057
- 0.0107 -
17_THR PRO 4.7kJPN
chr19:55106177
rs142517538
- 0.0196 -
20_SER ILE 4.7kJPN
chr19:54783873
-
- 0.0001 -
27_GLN TER 4.7kJPN
chr19:55143028
-
- 0.0001 -
28_GLY ARG 4.7kJPN
chr19:55085848
rs1290067922
- 0.0001 -
36_HIS ARG 4.7kJPN
chr19:55085873
rs578056886
- 0.0001 -
36_ARG GLY 4.7kJPN
chr19:55143055
rs749592435
- 0.0007 -
40_GLU GLN 4.7kJPN
chr19:55106246
-
- 0.0001 -
45_LEU PRO 4.7kJPN
chr19:54803621
rs144909639
- 0.6847 -
47_ILE PHE 4.7kJPN
chr19:54783793
-
- 0.0001 -
51_ARG TER 4.7kJPN
chr19:54783781
rs1366546333
- 0.0001 -
53_GLU LYS 4.7kJPN
chr19:55085920
rs189159031
- 0.0001 -
54_ILE LEU 4.7kJPN
chr19:55106288
rs147848714
- 0.0003 -
54_LEU ILE 4.7kJPN
chr19:55143109
rs750501464
- 0.0003 -
60_PHE LEU 4.7kJPN
chr19:54803577
rs200659644
- 0.0019 -
63_LEU PRO 4.7kJPN
chr19:54803567
rs142556784
- 0.6841 -
64_SER CYS 4.7kJPN
chr19:55106319
-
- 0.0001 -
67_TRP GLY 4.7kJPN
chr19:54803556
-
- 0.0002 -
68_GLU LYS 4.7kJPN
chr19:54783730
rs1022457451
- 0.0004 -
70_ALA THR VAR_049888 rs12460501
Polymorphism - -
70_THR ALA 4.7kJPN
chr19:55106336
rs766834992
- 0.0001 -
71_GLY GLU 4.7kJPN
chr19:55085975
-
- 0.0002 -
72_ARG TER 4.7kJPN
chr19:54783718
rs746435174
- 0.0001 -
73_TYR CYS 4.7kJPN
chr19:55085981
-
- 0.0003 -
74_ARG CYS 4.7kJPN
chr19:55106348
rs780861027
- 0.0001 -
84_LEU ARG 4.7kJPN
chr19:54803504
rs6509862
- 0.9445 -
94_VAL MET 4.7kJPN
chr19:55106408
rs1361562599
- 0.0001 -
98_ALA THR 4.7kJPN
chr19:55086200
-
- 0.0001 -
100_SER ILE 4.7kJPN
chr19:54803309
rs779366390
- 0.0005 -
106_ALA VAL 4.7kJPN
chr19:55086225
-
- 0.0003 -
107_LEU GLN 4.7kJPN
chr19:54803288
-
- 0.0002 -
107_LEU GLN 4.7kJPN
chr19:55086228
rs780646104
- 0.0087 -
108_PRO SER 4.7kJPN
chr19:54803286
-
- 0.0019 -
110_PRO LEU 4.7kJPN
chr19:55086237
-
- 0.0001 -
113_THR ALA 4.7kJPN
chr19:54783455
rs768931745
- 0.0035 -
113_THR ALA 4.7kJPN
chr19:54803271
-
- 0.0002 -
113_THR ALA 4.7kJPN
chr19:55086245
rs777235606
- 0.0091 -
114_SER THR 4.7kJPN
chr19:55086248
-
- 0.0001 -
116_GLY GLU 4.7kJPN
chr19:54803261
rs751649447
- 0.0002 -
116_GLY GLU 4.7kJPN
chr19:55086255
rs780649717
- 0.0092 -
116_GLY ARG 4.7kJPN
chr19:55106621
-
- 0.0003 -
117_ARG THR 4.7kJPN
chr19:54783442
rs749531977
- 0.0024 -
120_ILE LEU 4.7kJPN
chr19:54803250
rs75159993
- 0.0002 -
123_GLU ASP 4.7kJPN
chr19:54783423
rs758035729
- 0.0016 -
123_GLU GLY 4.7kJPN
chr19:54783424
rs751291818
- 0.0017 -
123_ASP GLY 4.7kJPN
chr19:54803240
-
- 0.0002 -
123_VAL GLY 4.7kJPN
chr19:55086276
rs571423648
- 0.0091 -
125_GLN GLU 4.7kJPN
chr19:54803235
-
- 0.0005 -
126_VAL LEU 4.7kJPN
chr19:54803232
rs141580607
- 0.0553 -
127_ALA PRO 4.7kJPN
chr19:54783413
rs752410806
- 0.0015 -
127_ALA PRO 4.7kJPN
chr19:54803229
-
- 0.0002 -
127_ALA PRO 4.7kJPN
chr19:55086287
rs754386274
- 0.0088 -
128_PHE SER 4.7kJPN
chr19:54783409
rs147946414
- 0.0001 -
129_GLY ASP 4.7kJPN
chr19:54783406
rs201825609
- 0.0019 -
130_SER GLY 4.7kJPN
chr19:55106663
rs10417589
- 0.0013 -
136_GLU GLN 4.7kJPN
chr19:54783386
rs774796329
- 0.0018 -
136_GLU GLN 4.7kJPN
chr19:54803202
-
- 0.0002 -
136_GLU GLN 4.7kJPN
chr19:55086314
rs201199710
- 0.0074 -
136_GLU GLN 4.7kJPN
chr19:55106681
rs1167314659
- 0.0004 -
137_GLY GLU 4.7kJPN
chr19:54783382
rs763237443
- 0.0018 -
137_GLY GLU 4.7kJPN
chr19:54803198
-
- 0.0002 -
137_GLY GLU 4.7kJPN
chr19:55086318
rs981943540
- 0.0074 -
141_HIS TYR 4.7kJPN
chr19:55106696
rs75416770
- 0.0504 -
143_GLN GLU 4.7kJPN
chr19:55143523
rs763628392
- 0.0001 -
144_ARG CYS 4.7kJPN
chr19:55086338
rs149722559
- 0.006 -
148_HIS GLN 4.7kJPN
chr19:55086352
rs759834040
- 0.0068 -
148_GLN HIS 4.7kJPN
chr19:55143540
rs749158954
- 0.0002 -
149_SER PRO 4.7kJPN
chr19:55086353
rs765734952
- 0.0068 -
149_PRO SER 4.7kJPN
chr19:55143541
rs768734027
- 0.0002 -
154_SER TRP 4.7kJPN
chr19:54783331
rs576220286
- 0.0007 -
154_SER ALA 4.7kJPN
chr19:54783332
rs765998984
- 0.0004 -
154_TRP GLY 4.7kJPN
chr19:55086368
rs780051526
- 0.0064 -
155_SER PRO 4.7kJPN
chr19:54783329
rs555983101
- 0.0001 -
156_ARG HIS 4.7kJPN
chr19:54783325
rs765314039
- 0.0001 -
156_ARG CYS 4.7kJPN
chr19:54783326
rs775954639
- 0.0005 -
156_ARG TRP 4.7kJPN
chr19:55106741
rs201483250
- 0.0002 -
166_PRO ARG 4.7kJPN
chr19:54783295
rs752949543
- 0.0002 -
166_PRO ALA 4.7kJPN
chr19:55086404
rs754870024
- 0.0008 -
167_ASN SER 4.7kJPN
chr19:54783292
rs373341013
- 0.0006 -
168_ARG CYS 4.7kJPN
chr19:55106777
rs141328341
- 0.0001 -
168_ARG HIS 4.7kJPN
chr19:55106778
rs10418391
- 0.0002 -
171_SER TRP 4.7kJPN
chr19:55086420
rs770183945
- 0.0001 -
171_TRP TER 4.7kJPN
chr19:55143609
rs373103118
- 0.0072 -
172_HIS TYR 4.7kJPN
chr19:54783278
rs774001588
- 0.0003 -
175_TYR CYS 4.7kJPN
chr19:54783268
-
- 0.0002 -
176_GLY ALA 4.7kJPN
chr19:54803081
rs773860990
- 0.0002 -
176_ALA GLY 4.7kJPN
chr19:55086435
rs138740762
- 0.0063 -
176_ALA GLY 4.7kJPN
chr19:55106802
rs1339989721
- 0.0025 -
179_LEU SER 4.7kJPN
chr19:54783256
rs374882341
- 0.0003 -
179_SER LEU 4.7kJPN
chr19:55143632
rs200423268
- 0.0029 -
180_ASN SER 4.7kJPN
chr19:54783253
rs1189729658
- 0.0002 -
180_ARG HIS 4.7kJPN
chr19:54803069
rs147951028
- 0.6844 -
180_ASN SER 4.7kJPN
chr19:55086447
rs150674530
- 0.0064 -
180_ASN SER 4.7kJPN
chr19:55106814
rs776711765
- 0.0026 -
181_SER THR 4.7kJPN
chr19:55106816
-
- 0.0007 -
183_TYR HIS 4.7kJPN
chr19:55086455
rs138719779
- 0.0002 -
183_HIS TYR 4.7kJPN
chr19:55106822
rs150400481
- 0.0026 -
185_TRP TER 4.7kJPN
chr19:55086463
rs201934047
- 0.0031 -
186_SER PRO 4.7kJPN
chr19:55143652
-
- 0.0001 -
187_LEU VAL 4.7kJPN
chr19:55143655
-
- 0.0001 -
190_ASP GLU 4.7kJPN
chr19:55086478
rs752284633
- 0.0001 -
193_GLY GLU 4.7kJPN
chr19:54803030
rs142529349
- 0.6845 -
197_LEU PRO 4.7kJPN
chr19:55106865
rs373854
- 0.3146 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.