PDB ID 1G0X     CHAIN A
Protein name LEUCOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR-1
Uniprot Accession Q8NHL6
The number of similar proteins 11
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1G0X (CHAIN: A)
1 Monomeric state
2 Q8NHL6  
3 P61769   P01892  
4 P61769   Q4A1U8  

Downdload

Format:

Molecule viewer

#binding
partners
  2
  1
  0

Sequence information

1   HLPKPTLWAE   PGSVITQGSP   VTLRCQGGQE   TQEYRLYREK   KTAPWITRIP   50
51   QELVKKGQFP   IPSITWEHAG   RYRCYYGSDT   AGRSESSDPL   ELVVTGAYIK   100
101   PTLSAQPSPV   VNSGGNVTLQ   CDSQVAFDGF   ILCKEGEDEH   PQCLNSQPHA   150
151   RGSSRAIFSV   GPVSPSRRWW   YRCYAYDSNS   PYEWSLPSDL   LELLVLG   200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(4.7kJPN)		 Disease name
3_LEU ILE 4.7kJPN
chr19:54803748 		rs139099303
- 0.4055 -
17_THR ILE 4.7kJPN
chr19:54783882 		rs75728057
- 0.0107 -
17_THR PRO 4.7kJPN
chr19:55106177 		rs142517538
- 0.0196 -
20_SER ILE 4.7kJPN
chr19:54783873 		-
- 0.0001 -
27_GLN TER 4.7kJPN
chr19:55143028 		-
- 0.0001 -
28_GLY ARG 4.7kJPN
chr19:55085848 		rs1290067922
- 0.0001 -
36_HIS ARG 4.7kJPN
chr19:55085873 		rs578056886
- 0.0001 -
36_ARG GLY 4.7kJPN
chr19:55143055 		rs749592435
- 0.0007 -
40_GLU GLN 4.7kJPN
chr19:55106246 		-
- 0.0001 -
45_LEU PRO 4.7kJPN
chr19:54803621 		rs144909639
- 0.6847 -
47_ILE PHE 4.7kJPN
chr19:54783793 		-
- 0.0001 -
51_ARG TER 4.7kJPN
chr19:54783781 		rs1366546333
- 0.0001 -
53_GLU LYS 4.7kJPN
chr19:55085920 		rs189159031
- 0.0001 -
54_ILE LEU 4.7kJPN
chr19:55106288 		rs147848714
- 0.0003 -
54_LEU ILE 4.7kJPN
chr19:55143109 		rs750501464
- 0.0003 -
60_PHE LEU 4.7kJPN
chr19:54803577 		rs200659644
- 0.0019 -
63_LEU PRO 4.7kJPN
chr19:54803567 		rs142556784
- 0.6841 -
64_SER CYS 4.7kJPN
chr19:55106319 		-
- 0.0001 -
67_TRP GLY 4.7kJPN
chr19:54803556 		-
- 0.0002 -
68_GLU LYS 4.7kJPN
chr19:54783730 		rs1022457451
- 0.0004 -
70_ALA THR VAR_049888 rs12460501
Polymorphism - -
70_THR ALA 4.7kJPN
chr19:55106336 		rs766834992
- 0.0001 -
71_GLY GLU 4.7kJPN
chr19:55085975 		-
- 0.0002 -
72_ARG TER 4.7kJPN
chr19:54783718 		rs746435174
- 0.0001 -
73_TYR CYS 4.7kJPN
chr19:55085981 		-
- 0.0003 -
74_ARG CYS 4.7kJPN
chr19:55106348 		rs780861027
- 0.0001 -
84_LEU ARG 4.7kJPN
chr19:54803504 		rs6509862
- 0.9445 -
94_VAL MET 4.7kJPN
chr19:55106408 		rs1361562599
- 0.0001 -
98_ALA THR 4.7kJPN
chr19:55086200 		-
- 0.0001 -
100_SER ILE 4.7kJPN
chr19:54803309 		rs779366390
- 0.0005 -
106_ALA VAL 4.7kJPN
chr19:55086225 		-
- 0.0003 -
107_LEU GLN 4.7kJPN
chr19:54803288 		-
- 0.0002 -
107_LEU GLN 4.7kJPN
chr19:55086228 		rs780646104
- 0.0087 -
108_PRO SER 4.7kJPN
chr19:54803286 		-
- 0.0019 -
110_PRO LEU 4.7kJPN
chr19:55086237 		-
- 0.0001 -
113_THR ALA 4.7kJPN
chr19:54783455 		rs768931745
- 0.0035 -
113_THR ALA 4.7kJPN
chr19:54803271 		-
- 0.0002 -
113_THR ALA 4.7kJPN
chr19:55086245 		rs777235606
- 0.0091 -
114_SER THR 4.7kJPN
chr19:55086248 		-
- 0.0001 -
116_GLY GLU 4.7kJPN
chr19:54803261 		rs751649447
- 0.0002 -
116_GLY GLU 4.7kJPN
chr19:55086255 		rs780649717
- 0.0092 -
116_GLY ARG 4.7kJPN
chr19:55106621 		-
- 0.0003 -
117_ARG THR 4.7kJPN
chr19:54783442 		rs749531977
- 0.0024 -
120_ILE LEU 4.7kJPN
chr19:54803250 		rs75159993
- 0.0002 -
123_GLU ASP 4.7kJPN
chr19:54783423 		rs758035729
- 0.0016 -
123_GLU GLY 4.7kJPN
chr19:54783424 		rs751291818
- 0.0017 -
123_ASP GLY 4.7kJPN
chr19:54803240 		-
- 0.0002 -
123_VAL GLY 4.7kJPN
chr19:55086276 		rs571423648
- 0.0091 -
125_GLN GLU 4.7kJPN
chr19:54803235 		-
- 0.0005 -
126_VAL LEU 4.7kJPN
chr19:54803232 		rs141580607
- 0.0553 -
127_ALA PRO 4.7kJPN
chr19:54783413 		rs752410806
- 0.0015 -
127_ALA PRO 4.7kJPN
chr19:54803229 		-
- 0.0002 -
127_ALA PRO 4.7kJPN
chr19:55086287 		rs754386274
- 0.0088 -
128_PHE SER 4.7kJPN
chr19:54783409 		rs147946414
- 0.0001 -
129_GLY ASP 4.7kJPN
chr19:54783406 		rs201825609
- 0.0019 -
130_SER GLY 4.7kJPN
chr19:55106663 		rs10417589
- 0.0013 -
136_GLU GLN 4.7kJPN
chr19:54783386 		rs774796329
- 0.0018 -
136_GLU GLN 4.7kJPN
chr19:54803202 		-
- 0.0002 -
136_GLU GLN 4.7kJPN
chr19:55086314 		rs201199710
- 0.0074 -
136_GLU GLN 4.7kJPN
chr19:55106681 		rs1167314659
- 0.0004 -
137_GLY GLU 4.7kJPN
chr19:54783382 		rs763237443
- 0.0018 -
137_GLY GLU 4.7kJPN
chr19:54803198 		-
- 0.0002 -
137_GLY GLU 4.7kJPN
chr19:55086318 		rs981943540
- 0.0074 -
141_HIS TYR 4.7kJPN
chr19:55106696 		rs75416770
- 0.0504 -
143_GLN GLU 4.7kJPN
chr19:55143523 		rs763628392
- 0.0001 -
144_ARG CYS 4.7kJPN
chr19:55086338 		rs149722559
- 0.006 -
148_HIS GLN 4.7kJPN
chr19:55086352 		rs759834040
- 0.0068 -
148_GLN HIS 4.7kJPN
chr19:55143540 		rs749158954
- 0.0002 -
149_SER PRO 4.7kJPN
chr19:55086353 		rs765734952
- 0.0068 -
149_PRO SER 4.7kJPN
chr19:55143541 		rs768734027
- 0.0002 -
154_SER TRP 4.7kJPN
chr19:54783331 		rs576220286
- 0.0007 -
154_SER ALA 4.7kJPN
chr19:54783332 		rs765998984
- 0.0004 -
154_TRP GLY 4.7kJPN
chr19:55086368 		rs780051526
- 0.0064 -
155_SER PRO 4.7kJPN
chr19:54783329 		rs555983101
- 0.0001 -
156_ARG HIS 4.7kJPN
chr19:54783325 		rs765314039
- 0.0001 -
156_ARG CYS 4.7kJPN
chr19:54783326 		rs775954639
- 0.0005 -
156_ARG TRP 4.7kJPN
chr19:55106741 		rs201483250
- 0.0002 -
166_PRO ARG 4.7kJPN
chr19:54783295 		rs752949543
- 0.0002 -
166_PRO ALA 4.7kJPN
chr19:55086404 		rs754870024
- 0.0008 -
167_ASN SER 4.7kJPN
chr19:54783292 		rs373341013
- 0.0006 -
168_ARG CYS 4.7kJPN
chr19:55106777 		rs141328341
- 0.0001 -
168_ARG HIS 4.7kJPN
chr19:55106778 		rs10418391
- 0.0002 -
171_SER TRP 4.7kJPN
chr19:55086420 		rs770183945
- 0.0001 -
171_TRP TER 4.7kJPN
chr19:55143609 		rs373103118
- 0.0072 -
172_HIS TYR 4.7kJPN
chr19:54783278 		rs774001588
- 0.0003 -
175_TYR CYS 4.7kJPN
chr19:54783268 		-
- 0.0002 -
176_GLY ALA 4.7kJPN
chr19:54803081 		rs773860990
- 0.0002 -
176_ALA GLY 4.7kJPN
chr19:55086435 		rs138740762
- 0.0063 -
176_ALA GLY 4.7kJPN
chr19:55106802 		rs1339989721
- 0.0025 -
179_LEU SER 4.7kJPN
chr19:54783256 		rs374882341
- 0.0003 -
179_SER LEU 4.7kJPN
chr19:55143632 		rs200423268
- 0.0029 -
180_ASN SER 4.7kJPN
chr19:54783253 		rs1189729658
- 0.0002 -
180_ARG HIS 4.7kJPN
chr19:54803069 		rs147951028
- 0.6844 -
180_ASN SER 4.7kJPN
chr19:55086447 		rs150674530
- 0.0064 -
180_ASN SER 4.7kJPN
chr19:55106814 		rs776711765
- 0.0026 -
181_SER THR 4.7kJPN
chr19:55106816 		-
- 0.0007 -
183_TYR HIS 4.7kJPN
chr19:55086455 		rs138719779
- 0.0002 -
183_HIS TYR 4.7kJPN
chr19:55106822 		rs150400481
- 0.0026 -
185_TRP TER 4.7kJPN
chr19:55086463 		rs201934047
- 0.0031 -
186_SER PRO 4.7kJPN
chr19:55143652 		-
- 0.0001 -
187_LEU VAL 4.7kJPN
chr19:55143655 		-
- 0.0001 -
190_ASP GLU 4.7kJPN
chr19:55086478 		rs752284633
- 0.0001 -
193_GLY GLU 4.7kJPN
chr19:54803030 		rs142529349
- 0.6845 -
197_LEU PRO 4.7kJPN
chr19:55106865 		rs373854
- 0.3146 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.