PDB ID 1ES7     CHAIN A
Protein name BONE MORPHOGENETIC PROTEIN-2
Uniprot Accession P12643
The number of similar proteins 26
The number of binding states 10
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer

#binding
partners
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MAQAKHKQRK   RLKSSCKRHP   LYVDFSDVGW   NDWIVAPPGY   HAFYCHGECP   50
51   FPLADHLNST   NHAIVQTLVN   SVNSKIPKAC   CVPTELSAIS   MLYLDENEKV   100
101   VLKNYQDMVV   EGCGCR         150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
15_ARG TRP 4.7kJPN
chr14:54417052
rs745803587
- 0.0001 -
18_PRO THR 4.7kJPN
chr20:6759443
rs1455627279
- 0.0002 -
47_CYS TER ClinVar
chr20:6759532
rs1555786156
Pathogenic - SHORT STATURE, FACIAL DYSMORPHISM, AND SKELETAL ANOMALIES WITH OR WITHOUT CARDIAC ANOMALIES [MedGen:C4693481,OMIM:617877]
52_ALA VAL ClinVar
chr14:54416940
rs121912766
Pathogenic - Orofacial cleft 11 [MedGen:C2677434,OMIM:600625]
74_ILE VAL 4.7kJPN
chr20:6759611
-
- 0.0001 -
105_ASP GLY VAR_052570 rs11545591
Polymorphism - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.