PDB ID 1EJL     CHAIN I
Protein name IMPORTIN ALPHA
Uniprot Accession P52293
The number of similar proteins 86
The number of binding states 14
The number of binding partners 13

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1EJL (CHAIN: I)
1 Monomeric state
2 P18887  
3 P31345  
4 Q9UGN5  
5 P34160  
6 B6VDJ7  
7 Q32ZE1  
8 P0C1C7  
9 Q9I8N0  
10 P52591  
11 Q09161  
12 Q15020  
13 Q9JIH2  
14 3TPM  

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#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   NQGTVNWSVE   DIVKGINSNN   LESQLQATQA   ARKLLSREKQ   PPIDNIIRAG   50
51   LIPKFVSFLG   KTDCSPIQFE   SAWALTNIAS   GTSEQTKAVV   DGGAIPAFIS   100
101   LLASPHAHIS   EQAVWALGNI   AGDGSAFRDL   VIKHGAIDPL   LALLAVPDLS   150
151   TLACGYLRNL   TWTLSNLCRN   KNPAPPLDAV   EQILPTLVRL   LHHNDPEVLA   200
201   DSCWAISYLT   DGPNERIEMV   VKKGVVPQLV   KLLGATELPI   VTPALRAIGN   250
251   IVTGTDEQTQ   KVIDAGALAV   FPSLLTNPKT   NIQKEATWTM   SNITAGRQDQ   300
301   IQQVVNHGLV   PFLVGVLSKA   DFKTQKEAAW   AITNYTSGGT   VEQIVYLVHC   350
351   GIIEPLMNLL   SAKDTKIIQV   ILDAISNIFQ   AAEKLGETEK   LSIMIEECGG   400
401   LDKIEALQRH   ENESVYKASL   NLIEKYFSVE   EEEDQNVVPE   TTSEGFAFQV   450
451   QDGAPGTFNF           500

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
99_ALA GLY 4.7kJPN
chr17:66036876
rs782062469
- 0.0001 -
114_ASN LYS 4.7kJPN
chr17:66038240
-
- 0.0002 -
132_ASP TYR 4.7kJPN
chr17:66038292
-
- 0.0001 -
155_THR SER 4.7kJPN
chr17:66038362
rs142601381
- 0.0004 -
183_VAL PHE 4.7kJPN
chr17:66038445
-
- 0.0003 -
194_SER LEU 4.7kJPN
chr17:66039030
-
- 0.0001 -
227_ARG CYS 4.7kJPN
chr17:66039228
rs782396125
- 0.0001 -
244_PRO SER 4.7kJPN
chr17:66039279
rs146139322
- 0.0001 -
285_ARG GLN 4.7kJPN
chr17:66039403
rs781877143
- 0.0021 -
334_ALA VAL 4.7kJPN
chr17:66040024
-
- 0.0001 -
356_THR MET 4.7kJPN
chr17:66040090
rs138064111
- 0.0041 -
366_ARG CYS 4.7kJPN
chr17:66040119
rs202041693
- 0.0009 -
465_GLU ALA 4.7kJPN
chr17:66041934
-
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.