PDB ID 1EBA     CHAIN A
Protein name PROTEIN (ERYTHROPOIETIN RECEPTOR)
Uniprot Accession P19235
The number of similar proteins 19
The number of binding states 8
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   KFESKAALLA   ARGPEELLCF   TERLEDLVCF   WEEAASAGVG   PGNYSFSYQL   50
51   EDEPWKLCRL   HQAPTARGAV   RFWCSLPTAD   TSSFVPLELR   VTAASGAPRY   100
101   HRVIHINEVV   LLDAPVGLVA   RLADESGHVV   LRWLPPPETP   MTSHIRYEVD   150
151   VSAGNGAGSV   QRVEILEGRT   ECVLSNLRGR   TRYTFAVRAR   MAEPSFGGFW   200
201   SAWSEPVSLL   TPSDL         250

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
21_ARG TRP 4.7kJPN
chr19:11493891
rs751506215
- 0.0001 -
48_VAL ALA 4.7kJPN
chr19:11493809
rs780617943
- 0.0001 -
58_GLN TER ClinVar
chr19:11493780
rs370865377
Likely pathogenic - not provided [MedGen:CN517202]
58_GLN ARG 4.7kJPN
chr19:11493779
rs1218322679
- 0.0001 -
68_ARG PRO 4.7kJPN
chr19:11492758
-
- 0.0001 -
113_ILE VAL 4.7kJPN
chr19:11492624
-
- 0.0001 -
129_ALA VAL 4.7kJPN
chr19:11492495
rs758156767
- 0.0001 -
132_ALA VAL 4.7kJPN
chr19:11492486
-
- 0.0001 -
138_VAL ILE 4.7kJPN
chr19:11492469
-
- 0.0001 -
158_VAL LEU 4.7kJPN
chr19:11492409
rs1326443454
- 0.0002 -
160_VAL ILE 4.7kJPN
chr19:11492403
-
- 0.0002 -
180_GLU ASP 4.7kJPN
chr19:11491859
-
- 0.0001 -
188_GLY CYS 4.7kJPN
chr19:11491837
rs185740642
- 0.0068 -
215_PRO THR 4.7kJPN
chr19:11491756
rs765522005
- 0.0021 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.