PDB ID 1CSG     CHAIN A
Protein name Granulocyte-macrophage colony-stimulating factor
Uniprot Accession P04141
The number of similar proteins 11
The number of binding states 5
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1CSG (CHAIN: A)
1 P04141  
2 Monomeric state
3 P15509  
4 P15509   P32927  
5 5C7X   5C7X  

Downdload

Format:

Molecule viewer

#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   APARSPSPST   QPWEHVNAIQ   EARRLLNLSR   DTAAEMNETV   EVISEMFDLQ   50
51   EPTCLQTRLE   LYKQGLRGSL   TKLKGPLTMM   ASHYKQHCPP   TPETSCATQI   100
101   ITFESFKENL   KDFLLVIPFD   CWEPVQE       150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
20_GLN HIS 4.7kJPN
chr5:131409627
-
- 0.0001 -
23_ARG TRP 4.7kJPN
chr5:131409634
rs1224453147
- 0.0002 -
24_ARG HIS 4.7kJPN
chr5:131409638
rs200145269
- 0.0001 -
78_THR ILE 4.7kJPN
chr5:131410585
-
- 0.0001 -
87_HIS GLN 4.7kJPN
chr5:131410613
-
- 0.0001 -
98_THR ILE VAR_013089 rs2069640
Polymorphism - -
100_ILE THR VAR_001975 rs25882
Polymorphism - -
100_ILE THR 4.7kJPN
chr5:131411460
rs25882
- 0.5894 -
101_ILE THR 4.7kJPN
chr5:131411463
-
- 0.0002 -
102_THR ASN 4.7kJPN
chr5:131411466
rs755412035
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.