PDB ID 1CSG     CHAIN A
Protein name Granulocyte-macrophage colony-stimulating factor
Uniprot Accession P04141
The number of similar proteins 11
The number of binding states 5
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1CSG (CHAIN: A)
1 P04141  
2 Monomeric state
3 P15509  
4 P15509   P32927  
5 5C7X   5C7X  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   APARSPSPST   QPWEHVNAIQ   EARRLLNLSR   DTAAEMNETV   EVISEMFDLQ   50
51   EPTCLQTRLE   LYKQGLRGSL   TKLKGPLTMM   ASHYKQHCPP   TPETSCATQI   100
101   ITFESFKENL   KDFLLVIPFD   CWEPVQE       150

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
20_GLN HIS 8.3kJPN
chr5:131409627 		-
- 0.0001 -
23_ARG TRP 8.3kJPN
chr5:131409634 		rs1224453147
- 0.0003 -
24_ARG HIS gnomAD
chr5:131409638 		rs200145269
- 0.000111542 -
24_ARG HIS 8.3kJPN
chr5:131409638 		rs200145269
- 0.0001 -
78_THR ILE 8.3kJPN
chr5:131410585 		-
- 0.0001 -
87_HIS GLN 8.3kJPN
chr5:131410613 		-
- 0.0001 -
98_THR ILE VAR_013089 rs2069640
LB/B - -
98_THR ILE gnomAD
chr5:131411454 		rs2069640
- 0.00128431 -
100_ILE THR VAR_001975 rs25882
LB/B - -
100_ILE THR gnomAD
chr5:131411460 		rs25882
- 0.26468 -
100_ILE THR 8.3kJPN
chr5:131411460 		rs25882
- 0.5916 -
101_ILE THR 8.3kJPN
chr5:131411463 		-
- 0.0002 -
102_THR ASN 8.3kJPN
chr5:131411466 		rs755412035
- 0.0001 -
(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.