PDB ID 1C3D     CHAIN A
Protein name C3D
Uniprot Accession P01024
The number of similar proteins 20
The number of binding states 9
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1C3D (CHAIN: A)
1 Monomeric state
2 C8LN82  
3 P20023  
4 P08603  
5 Q99UV2  
6 P11215  
7 P20023   P20023  
8 P01024   P08603  
9 P01024   P01024   Q99UV2  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MLDAERLKHL   IVTPSGAGEQ   NMIGMTPTVI   AVHYLDETEQ   WEKFGLEKRQ   50
51   GALELIKKGY   TQQLAFRQPS   SAFAAFVKRA   PSTWLTAYVV   KVFSLAVNLI   100
101   AIDSQVLCGA   VKWLILEKQK   PDGVFQEDAP   VIHQEMIGGL   RNNNEKDMAL   150
151   TAFVLISLQE   AKDICEEQVN   SLPGSITKAG   DFLEANYMNL   QRSYTVAIAG   200
201   YALAQMGRLK   GPLLNKFLTT   AKDKNRWEDP   GKQLYNVEAT   SYALLALLQL   250
251   KDFDFVPPVV   RWLNEQRYYG   GGYGSTQATF   MVFQALAQYQ   KDAP   300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
20_GLN HIS 8.3kJPN
chr19:6694557 		-
- 0.0001 -
24_GLY CYS 8.3kJPN
chr19:6694547 		-
- 0.0003 -
49_ARG LEU VAR_063655 -
Disease - Hemolytic uremic syndrome atypical 5 (AHUS5) [MIM:612925]
101_ALA VAL VAR_063216 rs121909584
Disease - Hemolytic uremic syndrome atypical 5 (AHUS5) [MIM:612925]
122_ASP ASN VAR_063217 rs121909585
Disease - Hemolytic uremic syndrome atypical 5 (AHUS5) [MIM:612925]
141_ARG GLN 8.3kJPN
chr19:6690728 		rs777904423
- 0.0001 -
151_THR ALA 8.3kJPN
chr19:6690699 		-
- 0.0001 -
165_CYS TRP VAR_063218 -
Disease - Hemolytic uremic syndrome atypical 5 (AHUS5) [MIM:612925]
168_GLN LYS VAR_063219 -
Disease - Hemolytic uremic syndrome atypical 5 (AHUS5) [MIM:612925]
231_GLY ASP VAR_019207 rs11569534
Polymorphism - -
231_GLY ASP gnomAD
chr19:6686274 		rs11569534
- 0.00147915 -
259_VAL ILE gnomAD
chr19:6686191 		rs537300095
- 0.000258453 -
259_VAL ILE 8.3kJPN
chr19:6686191 		rs537300095
- 0.0001 -
270_GLY ALA 8.3kJPN
chr19:6686157 		-
- 0.0001 -
278_ALA SER 8.3kJPN
chr19:6685157 		-
- 0.0001 -
293_ALA THR 8.3kJPN
chr19:6685112 		rs556995881
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.