PDB ID 1BCC     CHAIN B
Protein name UBIQUINOL CYTOCHROME C OXIDOREDUCTASE
Uniprot Accession P23004
The number of similar proteins 31
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1BCC (CHAIN: B)
1 P23004   P00129   P13272  
2 2BCC  
3 P31800   P13272  
4 P23004   1SQP   P31800   P13272  

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Format:

Molecule viewer

#binding
partners
  2
  1
  0

Sequence information

1   PPHPQDLEIT   KLPNGLVIAS   LENYSPGSTI   GVFIKAGSRY   ENSSNLGTSH   50
51   LLRLASSLTT   KGASSFKITR   GIEAVGGKLS   VESTRENMAY   TVECLRDDVE   100
101   ILMEFLLNVT   TAPEFRPWEV   ADLQPQLKID   KAVAFQNPQT   HVIENLHAAA   150
151   YRNALADSLY   CPDYRIGKVT   SVELHDFVQN   HFTSARMALV   GLGVSHPVLK   200
201   NVAEQLLNIR   GGLGLSGAKA   KYRGGEIREQ   NGDSLVHAAI   VAESAAIGGA   250
251   EANAFSVLQH   VLGANPHVKR   GLNATSSLYQ   AVAKGVHNPF   DVSAFNASYS   300
301   DSGLFGFYTI   SQAAYAGQVI   KAAYNQVKTI   AQGNVSNENV   QAAKNKLKAK   350
351   YLMSVESSEG   FLEEVGSQAL   AAGSYNPPST   VLQQIDAVAD   ADVIKAAKKF   400
401   VSRQKSMAAS   GNLGHTPFVD   EL       450

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(4.7kJPN)		 Disease name
52_LYS GLN 4.7kJPN
chr16:21968816 		-
- 0.0001 -
62_ASN SER 4.7kJPN
chr16:21968847 		rs775768534
- 0.0001 -
70_ARG HIS 4.7kJPN
chr16:21968871 		rs371099781
- 0.0001 -
106_ALA VAL 4.7kJPN
chr16:21973807 		-
- 0.0003 -
107_TYR HIS ClinVar
chr16:21973809 		rs778618710
Likely pathogenic - not provided [MedGen:CN517202]
120_MET ILE 4.7kJPN
chr16:21974094 		rs898449154
- 0.0001 -
144_LEU ILE 4.7kJPN
chr16:21974164 		-
- 0.0001 -
155_PRO LEU 4.7kJPN
chr16:21974198 		rs1158265207
- 0.0001 -
169_ARG TRP ClinVar
chr16:21976761 		rs374661051
Pathogenic - Mitochondrial complex III deficiency, nuclear type 5 [MedGen:C3554608,OMIM:615160]
183_ILE PHE 4.7kJPN
chr16:21976803 		-
- 0.0001 -
225_ASN SER 4.7kJPN
chr16:21982891 		-
- 0.0003 -
245_ARG GLN 4.7kJPN
chr16:21983253 		rs780855199
- 0.0003 -
305_GLN PRO 4.7kJPN
chr16:21983433 		-
- 0.0001 -
356_ASP ASN 4.7kJPN
chr16:21987548 		-
- 0.0001 -
368_TYR CYS 4.7kJPN
chr16:21991888 		rs139312246
- 0.0175 -
388_VAL ILE 4.7kJPN
chr16:21991947 		rs1233348558
- 0.0001 -
403_ASP GLU 4.7kJPN
chr16:21991994 		-
- 0.0001 -
405_VAL MET 4.7kJPN
chr16:21991998 		rs748748050
- 0.0014 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.