PDB ID 1ARL     CHAIN A
Protein name APO-CARBOXYPEPTIDASE A=ALPHA= (COX)
Uniprot Accession P00730
The number of similar proteins 39
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1ARL (CHAIN: A)
1 Monomeric state
2 58374130  
3 P00730  
4 P01075  
5 P00730   P00730  
6 1PYT   P00730  
7 P00730   P81511   P81511  

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Molecule viewer

#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   ARSTNTFNYA   TYHTLDEIYD   FMDLLVAEHP   QLVSKLQIGR   SYEGRPIYVL   50
51   KFSTGGSNRP   AIWIDLGIHS   REWITQATGV   WFAKKFTEDY   GQDPSFTAIL   100
101   DSMDIFLEIV   TNPDGFAFTH   SQNRLWRKTR   SVTSSSLCVG   VDANRNWDAG   150
151   FGKAGASSSP   CSETYHGKYA   NSEVEVKSIV   DFVKDHGNFK   AFLSIHSYSQ   200
201   LLLYPYGYTT   QSIPDKTELN   QVAKSAVAAL   KSLYGTSYKY   GSIITTIYQA   250
251   SGGSIDWSYN   QGIKYSFTFE   LRDTGRYGFL   LPASQIIPTA   QETWLGVLTI   300
301   MEHTVNN           350

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
5_ASP ASN 4.7kJPN
chr7:130021666
rs782573440
- 0.0006 -
27_ALA GLY 4.7kJPN
chr7:130021977
rs183429188
- 0.0026 -
30_PRO ARG 4.7kJPN
chr7:130021986
-
- 0.0005 -
54_THR MET 4.7kJPN
chr7:130023239
rs781903028
- 0.0001 -
71_ARG GLN 4.7kJPN
chr7:130023290
rs377042960
- 0.0001 -
110_VAL ILE 4.7kJPN
chr7:130023597
-
- 0.0002 -
159_ASN LYS 4.7kJPN
chr7:130025006
rs782284797
- 0.0001 -
160_PRO LEU 4.7kJPN
chr7:130025008
-
- 0.0001 -
231_ALA THR 4.7kJPN
chr7:130025713
rs77792157
- 0.0571 -
255_ILE THR 4.7kJPN
chr7:130027686
-
- 0.0001 -
260_SER GLY 4.7kJPN
chr7:130027700
-
- 0.0001 -
260_SER ASN 4.7kJPN
chr7:130027701
-
- 0.0001 -
267_PHE TYR 4.7kJPN
chr7:130027722
-
- 0.0001 -
272_ARG GLN 4.7kJPN
chr7:130027737
rs782284762
- 0.0001 -
276_ARG CYS 4.7kJPN
chr7:130027748
rs201750163
- 0.0001 -
280_LEU MET 4.7kJPN
chr7:130027760
-
- 0.0001 -
284_SER THR 4.7kJPN
chr7:130027772
-
- 0.0001 -
284_SER TYR 4.7kJPN
chr7:130027773
-
- 0.0001 -
287_ILE LEU 4.7kJPN
chr7:130027781
-
- 0.0001 -
287_ILE MET 4.7kJPN
chr7:130027783
-
- 0.0001 -
298_LEU MET 4.7kJPN
chr7:130027814
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.