PDB ID 1D0G     CHAIN R
Protein name DEATH RECEPTOR-5
Uniprot Accession O14763
The number of similar proteins 18
The number of binding states 8
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1D0G (CHAIN: R)
1 P50591   P50591  
2 Q6RJQ3  
3 P50591  
4 1ZA3   1ZA3  
5 3X3F   3X3F  
6 O14763   O14763  
7 4N90   4N90   P50591  
8 6T3J   6T3J   6T3J   6T3J  

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Only interaction residues
#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   ALITQQDLAP   QQRAAPQQKR   SSPSEGLCPP   GHHISEDGRD   CISCKYGQDY   50
51   STHWNDLLFC   LRCTRCDSGE   VELSPCTTTR   NTVCQCEEGT   FREEDSPEMC   100
101   RKCRTGCPRG   MVKVGDCTPW   SDIECVHKES       150

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
30_PRO SER 8.3kJPN
chr8:22900654 		-
- 0.0001 -
62_ARG CYS 8.3kJPN
chr8:22888293 		rs770524322
- 0.0001 -
64_THR ILE 8.3kJPN
chr8:22888286 		-
- 0.0002 -
69_GLY SER 8.3kJPN
chr8:22888272 		rs1444006103
- 0.0001 -
78_THR MET 8.3kJPN
chr8:22887207 		rs759407943
- 0.0001 -
87_GLU LYS 8.3kJPN
chr8:22887181 		rs761287157
- 0.0002 -
96_SER PHE gnomAD
chr8:22887153 		rs541556717
- 0.000188359 -
101_ARG TRP 8.3kJPN
chr8:22887139 		rs755099736
- 0.0001 -
106_GLY VAL 8.3kJPN
chr8:22887123 		rs184681902
- 0.0004 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.