PDB ID 1A02     CHAIN N
Protein name NUCLEAR FACTOR OF ACTIVATED T CELLS
Uniprot Accession Q13469
The number of similar proteins 13
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1A02 (CHAIN: N)
1 P05412   P01100  
2 Monomeric state
3 Q13469  
4 O15409  
5 Q9BZS1   Q9BZS1  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   MRGSHHHHHH   TDPHASSVPL   EWPLSSQSGS   YELRIEVQPK   PHHRAHYETE   50
51   GSRGAVKAPT   GGHPVVQLHG   YMENKPLGLQ   IFIGTADERI   LKPHAFYQVH   100
101   RITGKTVTTT   SYEKIVGNTK   VLEIPLEPKN   NMRATIDCAG   ILKLRNADIE   150
151   LRKGETDIGR   KNTRVRLVFR   VHIPESSGRI   VSLQTASNPI   ECSQRSAHEL   200
201   PMVERQDTDS   CLVYGGQQMI   LTGQNFTSES   KVVFTEKTTD   GQQIWEMEAT   250
251   VDKDKSQPNM   LFVEIPEYRN   KHIRTPVKVN   FYVINGKRKR   SQPQHFTYHP   300
301   V           350

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
411_ARG GLN gnomAD
chr20:50133423
rs199662497
- 0.000107444 -
413_GLU LYS gnomAD
chr20:50133418
rs371590547
- 0.000103474 -
446_HIS ARG VAR_051783 rs12479626
LB/B - -
446_HIS ARG gnomAD
chr20:50092193
rs12479626
- 0.00978215 -
446_HIS ARG 8.3kJPN
chr20:50092193
rs12479626
- 0.0453 -
449_MET VAL gnomAD
chr20:50092185
rs137943373
- 0.000278445 -
466_ARG GLN 8.3kJPN
chr20:50092133
rs753566031
- 0.0001 -
478_ARG GLN 8.3kJPN
chr20:50092097
rs748148486
- 0.0001 -
485_THR SER gnomAD
chr20:50092077
rs181122021
- 0.000417512 -
485_THR SER 8.3kJPN
chr20:50092077
rs181122021
- 0.0006 -
492_ILE MET gnomAD
chr20:50092054
rs55799521
- 0.000186885 -
492_ILE MET 8.3kJPN
chr20:50092054
rs55799521
- 0.0007 -
502_PRO ARG 8.3kJPN
chr20:50092025
-
- 0.0005 -
558_VAL ILE 8.3kJPN
chr20:50090553
rs533808723
- 0.0001 -
579_MET THR gnomAD
chr20:50071198
rs201940278
- 0.000612594 -
587_SER ASN 8.3kJPN
chr20:50071174
-
- 0.0001 -
593_GLY SER gnomAD
chr20:50071157
rs199959483
- 0.000401661 -
627_THR MET 8.3kJPN
chr20:50052268
rs150751377
- 0.001 -
646_ARG TRP gnomAD
chr20:50051821
rs773542213
- 0.000226674 -
647_ASN SER 8.3kJPN
chr20:50051817
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.