| PDB ID | 1A02
|
CHAIN | N |
|---|---|---|---|
| Protein name | NUCLEAR FACTOR OF ACTIVATED T CELLS | ||
| Uniprot Accession | Q13469 | ||
| The number of similar proteins | 13 | ||
| The number of binding states | 5 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1A02 (CHAIN: N) | |
| 1 |
P05412
P01100
|
| 2 | Monomeric state |
| 3 |
Q13469
|
| 4 |
O15409
|
| 5 |
Q9BZS1
Q9BZS1
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 411_ARG | GLN |
gnomAD chr20:50133423 rs199662497 |
- | 0.000107444 | 0.0717 | - | |
| 413_GLU | LYS |
gnomAD chr20:50133418 rs371590547 |
- | 0.000103474 | 0.8349 | - | |
| 446_HIS | ARG |
VAR_051783
rs12479626 |
LB/B | - | 0.1304 | - | |
| 446_HIS | ARG |
gnomAD chr20:50092193 rs12479626 |
- | 0.00978215 | 0.1304 | - | |
| 446_HIS | ARG |
8.3kJPN chr20:50092193 rs12479626 |
- | 0.0453 | 0.1304 | - | |
| 449_MET | VAL |
gnomAD chr20:50092185 rs137943373 |
- | 0.000278445 | 0.0678 | - | |
| 466_ARG | GLN |
8.3kJPN chr20:50092133 rs753566031 |
- | 0.0001 | 0.797 | - | |
| 478_ARG | GLN |
8.3kJPN chr20:50092097 rs748148486 |
- | 0.0001 | 0.9876 | - | |
| 485_THR | SER |
gnomAD chr20:50092077 rs181122021 |
- | 0.000417512 | 0.2587 | - | |
| 485_THR | SER |
8.3kJPN chr20:50092077 rs181122021 |
- | 0.0006 | 0.2587 | - | |
| 492_ILE | MET |
gnomAD chr20:50092054 rs55799521 |
- | 0.000186885 | 0.0735 | - | |
| 492_ILE | MET |
8.3kJPN chr20:50092054 rs55799521 |
- | 0.0007 | 0.0735 | - | |
| 502_PRO | ARG |
8.3kJPN chr20:50092025 - |
- | 0.0005 | 0.9512 | - | |
| 558_VAL | ILE |
8.3kJPN chr20:50090553 rs533808723 |
- | 0.0001 | 0.0668 | - | |
| 579_MET | THR |
gnomAD chr20:50071198 rs201940278 |
- | 0.000612594 | 0.3581 | - | |
| 587_SER | ASN |
8.3kJPN chr20:50071174 - |
- | 0.0001 | 0.136 | - | |
| 593_GLY | SER |
gnomAD chr20:50071157 rs199959483 |
- | 0.000401661 | 0.463 | - | |
| 627_THR | MET |
8.3kJPN chr20:50052268 rs150751377 |
- | 0.001 | 0.1019 | - | |
| 646_ARG | TRP |
gnomAD chr20:50051821 rs773542213 |
- | 0.000226674 | 0.352 | - | |
| 647_ASN | SER |
8.3kJPN chr20:50051817 - |
- | 0.0001 | 0.1073 | - |