| PDB ID | 1EJL
|
CHAIN | I |
|---|---|---|---|
| Protein name | IMPORTIN ALPHA | ||
| Uniprot Accession | P52293 | ||
| The number of similar proteins | 149 | ||
| The number of binding states | 25 | ||
| The number of binding partners | 24 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1EJL (CHAIN: I) | |
| 1 | Monomeric state |
| 2 |
P18887
|
| 3 |
P31345
|
| 4 |
Q9UGN5
|
| 5 |
P34160
|
| 6 |
B6VDJ7
|
| 7 |
Q32ZE1
|
| 8 |
P0C1C7
|
| 9 |
P48431
|
| 10 |
P19838
|
| 11 |
C0LA97
|
| 12 |
Q01201
|
| 13 |
A0A2Z4K4X6
|
| 14 |
M4VRX3
|
| 15 |
B7MCR3
|
| 16 |
Q9I8N0
|
| 17 |
P52591
|
| 18 |
Q09161
|
| 19 |
P52292
|
| 20 |
8GAI
|
| 21 |
Q08379
|
| 22 |
Q16665
|
| 23 |
Q15020
|
| 24 |
Q9JIH2
|
| 25 |
3TPM
|
Downdload
Molecule viewer
|
Only interaction residues |
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|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 86_ASN | SER |
gnomAD chr17:66036837 rs142064368 |
- | 0.000274424 | - | - | |
| 99_ALA | GLY |
8.3kJPN chr17:66036876 rs782062469 |
- | 0.0001 | - | - | |
| 114_ASN | LYS |
8.3kJPN chr17:66038240 - |
- | 0.0002 | - | - | |
| 117_ARG | TRP |
gnomAD chr17:66038247 rs144637470 |
- | 0.00221403 | - | - | |
| 117_ARG | GLN |
gnomAD chr17:66038248 rs148032855 |
- | 0.00119055 | - | - | |
| 132_ASP | TYR |
8.3kJPN chr17:66038292 - |
- | 0.0001 | - | - | |
| 155_THR | SER |
8.3kJPN chr17:66038362 rs142601381 |
- | 0.0004 | - | - | |
| 165_PRO | ARG |
gnomAD chr17:66038392 rs11545989 |
- | 0.0036701 | - | - | |
| 173_SER | TYR |
8.3kJPN chr17:66038416 - |
- | 0.0001 | - | - | |
| 183_VAL | PHE |
8.3kJPN chr17:66038445 - |
- | 0.0002 | - | - | |
| 194_SER | LEU |
8.3kJPN chr17:66039030 rs1568276940 |
- | 0.0001 | - | - | |
| 216_PRO | SER |
gnomAD chr17:66039095 rs11545988 |
- | 0.00218697 | - | - | |
| 218_MET | THR |
gnomAD chr17:66039102 rs142968438 |
- | 0.000278346 | - | - | |
| 227_ARG | CYS |
8.3kJPN chr17:66039228 rs782396125 |
- | 0.0001 | - | - | |
| 244_PRO | THR |
gnomAD chr17:66039279 rs146139322 |
- | 0.000409869 | - | - | |
| 244_PRO | SER |
8.3kJPN chr17:66039279 rs146139322 |
- | 0.0001 | - | - | |
| 246_ILE | LEU |
8.3kJPN chr17:66039285 - |
- | 0.0001 | - | - | |
| 255_THR | SER |
gnomAD chr17:66039312 rs140011802 |
- | 0.000119331 | - | - | |
| 263_ASP | ALA |
gnomAD chr17:66039337 rs556496043 |
- | 0.000186892 | - | - | |
| 285_ARG | GLN |
gnomAD chr17:66039403 rs781877143 |
- | 0.000131216 | - | - | |
| 285_ARG | GLN |
8.3kJPN chr17:66039403 rs781877143 |
- | 0.0016 | - | - | |
| 329_GLN | TER |
8.3kJPN chr17:66040008 - |
- | 0.0001 | - | - | |
| 334_ALA | VAL |
8.3kJPN chr17:66040024 - |
- | 0.0001 | - | - | |
| 350_ASN | ASP |
8.3kJPN chr17:66040071 - |
- | 0.0001 | - | - | |
| 356_THR | MET |
gnomAD chr17:66040090 rs138064111 |
- | 0.000358226 | - | - | |
| 356_THR | MET |
8.3kJPN chr17:66040090 rs138064111 |
- | 0.0034 | - | - | |
| 366_ARG | CYS |
gnomAD chr17:66040119 rs202041693 |
- | 0.00017513 | - | - | |
| 366_ARG | CYS |
8.3kJPN chr17:66040119 rs202041693 |
- | 0.0011 | - | - | |
| 465_GLU | ALA |
8.3kJPN chr17:66041934 - |
- | 0.0002 | - | - |