PDB ID 6RPJ     CHAIN G
Protein name Cytotoxic T-lymphocyte protein 4
Uniprot Accession P16410
The number of similar proteins 20
The number of binding states 12
The number of binding partners 7

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
6RPJ (CHAIN: G)
1 6RPJ  
2 Monomeric state
3 P16410  
4 6RQM  
5 P33681  
6 3BX7  
7 7SU1   7SU1  
8 P16410   P42081  
9 7ELX   7ELX  
10 8HIT   8HIT  
11 P16410   7DV4  
12 P16410   7DV4   7DV4  

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Only interaction residues
#binding
partners
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   AMHVAQPAVV   LASSRGIASF   VCEYASPGKA   TEVRVTVLRQ   ADSQVTEVCA   50
51   ATYMMGNELT   FLDDSICTGT   SSGNQVNLTI   QGLRAMDTGL   YICKVELMYP   100
101   PPYYLGIGNG   TQIYVIDPEP   GGSHHHHHH       150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
35_ARG TRP VAR_072681
rs606231422
LP/P - 0.4657 Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation (IDAIL) [MIM:616100]
47_THR ILE 8.3kJPN
chr2:204735444
-
- 0.0001 0.1243 -
74_GLY GLU gnomAD
chr2:204735525
rs144988077
- 0.000227454 0.1276 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.