PDB ID 1OCC     CHAIN G
Protein name CYTOCHROME C OXIDASE
Uniprot Accession P07471
The number of similar proteins 104
The number of binding states 12
The number of binding partners 5

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   ASAAKGDHGG   TGARTWRFLT   FGLALPSVAL   CTLNSWLHSG   HRERPAFIPY   50
51   HHLRIRTKPF   SWGDGNHTFF   HNPRVNPLPT   GYEK     100

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
5_LYS ILE 8.3kJPN
chr16:31439597
-
- 0.0001 - -
27_SER ARG ClinVar
chr16:31439429
rs1597176845
Likely pathogenic - - Mitochondrial complex 4 deficiency, nuclear type 18 [MONDO:MONDO:0033653,MedGen:C5436720,OMIM:619062]
31_CYS ARG ClinVar
chr16:31439419
rs1275864234
Likely pathogenic - - Mitochondrial complex 4 deficiency, nuclear type 18 [MONDO:MONDO:0033653,MedGen:C5436720,OMIM:619062]
47_PHE LEU 8.3kJPN
chr16:31439369
-
- 0.0001 - -
57_THR SER 8.3kJPN
chr16:31439340
-
- 0.0002 - -
61_PRO ALA gnomAD
chr16:31439172
rs148307890
- 0.0002607 - -
75_VAL MET 8.3kJPN
chr16:31439130
-
- 0.0001 - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.