PiSITE

PDB ID	1BMF	CHAIN	G
Protein name	BOVINE MITOCHONDRIAL F1-ATPASE
Uniprot Accession	P05631
The number of similar proteins	29
The number of binding states	7
The number of binding partners	6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding state	Binding partners
	1BMF (CHAIN: G)
1	P00829 P00829 P00829 P19483 P19483 P19483
2	Monomeric state
3	P01096 P00829 P00829 P00829 P19483 P19483 P19483
4	P00829 P00829 P00829 P19483 P19483 P19483 P05632 P05630
5	P01096 P01096 P00829 P00829 P00829 P19483 P19483 P19483
6	P01096 P00829 P00829 P00829 Q1JQC4 Q1JQC4 Q1JQC4 P05632 P05630
7	P00829 P00829 P00829 P19483 P19483 P19483 P05632 P05630 P32876 P32876

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Molecule viewer

Only interaction residues

#binding
partners

	3
	2
	1
	0

Sequence information

ATLKDITRRL

KSIKNIQKIT

KSMKMVAAAK

YARAERELKP

ARVYGVGSLA

LYEKADIKTP

EDKKKHLIIG

VSSDRGLCGA

IHSSVAKQMK

SEAANLAAAG

100

101

KEVKIIGVGD

KIRSILHRTH

SDQFLVTFKE

VGRRPPTFGD

ASVIALELLN

150

151

SGYEFDEGSI

IFNRFRSVIS

YKTEEKPIFS

LDTISSAESM

SIYDDIDADV

200

201

LRNYQEYSLA

NIIYYSLKES

TTSEQSARMT

AMDNASKNAS

EMIDKLTLTF

250

251

NRTRQAVITK

ELIEIISGAA

300

Binding partner information

	P01096	ATPase inhibitor, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial

Binding partner information

	P00829	ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
	P00829	ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
	P00829	ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
	P19483	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL
	P19483	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL
	P19483	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL
	P05632	ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL
	P05630	F1-ATPASE DELTA SUBUNIT

Binding partner information

	P01096	ATPase inhibitor, mitochondrial
	P01096	ATPase inhibitor, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P00829	ATP synthase subunit beta, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial
	P19483	ATP synthase subunit alpha, mitochondrial

Binding partner information

	P01096	ATPASE INHIBITOR
	P00829	ATP SYNTHASE SUBUNIT BETA
	P00829	ATP SYNTHASE SUBUNIT BETA
	P00829	ATP SYNTHASE SUBUNIT BETA
	Q1JQC4	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM
	Q1JQC4	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM
	Q1JQC4	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM
	P05632	ATP SYNTHASE EPSILON CHAIN
	P05630	ATP SYNTHASE DELTA CHAIN

Variants

Residue	AA	Source / dbSNP	Clinical Significance	Allele Frequency (> 0.0001)	AlphaMissense pathogenicity	Disease name
2_THR	ALA	8.3kJPN chr10:7838106 rs199602842	-	0.0001	-	-
24_LYS	ARG	gnomAD chr10:7839064 rs755191204	-	0.000111381	-	-
37_GLU	GLN	8.3kJPN chr10:7839102 -	-	0.0001	-	-
40_PRO	SER	gnomAD chr10:7839111 rs199901078	-	0.00012729	-	-
240_SER	THR	8.3kJPN chr10:7844388 -	-	0.0001	-	-
253_THR	PRO	8.3kJPN chr10:7844759 -	-	0.0004	-	-

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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364