PDB ID 4F7U     CHAIN E
Protein name Small nuclear ribonucleoprotein E
Uniprot Accession P62305
The number of similar proteins 11
The number of binding states 7
The number of binding partners 7

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
4F7U (CHAIN: E)
1 P62309   P62321  
2 Monomeric state
3 P62306   O14893  
4 P62308   P62306   P62318  
5 P62308   P62306   O14893  
6 P62308   P62306   P62318   P08621  
7 P62308   P62306   Q9U3W1   Q9VVX0  

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Only interaction residues
#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   MAYRGQGQKV   QKVMVQPINL   IFRYLQNRSR   IQVWLYEQVN   MRIEGCIIGF   50
51   DEYMNLVLDD   AEEIHSKTKS   RKQLGRIMLK   GDNITLLQSV   SN   100

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
3045_GLY SER ClinVar
chr1:203832842
rs587776925
Pathogenic - - Hypotrichosis 11 [MONDO:MONDO:0014027,MedGen:C3554409,OMIM:615059,Orphanet:55654]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.