PDB ID 4JK1     CHAIN D
Protein name Escherichia coli RNA polymerase beta' subunit
Uniprot Accession P0A8T7
The number of similar proteins 59
The number of binding states 10
The number of binding partners 10

Molecule viewer


Only interaction residues
#binding
partners
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MKDLLKFLKA   QTKTEEFDAI   KIALASPDMI   RSWSFGEVKK   PETINYRTFK   50
51   PERDGLFCAR   IFGPVKDYEC   LCGKYKRLKH   RGVICEKCGV   EVTQTKVRRE   100
101   RMGHIELASP   TAHIWFLKSL   PSRIGLLLDM   PLRDIERVLY   FESYVVIEGG   150
151   MTNLERQQIL   TEEQYLDALE   EFGDEFDAKM   GAEAIQALLK   SMDLEQECEQ   200
201   LREELNETNS   ETKRKKLTKR   IKLLEAFVQS   GNKPEWMILT   VLPVLPPDLR   250
251   PLVPLDGGRF   ATSDLNDLYR   RVINRNNRLK   RLLDLAAPDI   IVRNEKRMLQ   300
301   EAVDALLDNG   RRGRAITGSN   KRPLKSLADM   IKGKQGRFRQ   NLLGKRVDYS   350
351   GRSVITVGPY   LRLHQCGLPK   KMALELFKPF   IYGKLELRGL   ATTIKAAKKM   400
401   VEREEAVVWD   ILDEVIREHP   VLLNRAPTLH   RLGIQAFEPV   LIEGKAIQLH   450
451   PLVCAAYNAD   FDGDQMAVHV   PLTLEAQLEA   RALMMSTNNI   LSPANGEPII   500
501   VPSQDVVLGL   YYMTRDCVNA   KGEGMVLTGP   KEAERLYRSG   LASLHARVKV   550
551   RITEYEKDAN   GELVAKTSLK   DTTVGRAILW   MIVPKGLPYS   IVNQALGKKA   600
601   ISKMLNTCYR   ILGLKPTVIF   ADQIMYTGFA   YAARSGASVG   IDDMVIPEKK   650
651   HEIISEAEAE   VAEIQEQFQS   GLVTAGERYN   KVIDIWAAAN   DRVSKAMMDN   700
701   LQTETVINRD   GQEEKQVSFN   SIYMMADSGA   RGSAAQIRQL   AGMRGLMAKP   750
751   DGSIIETPIT   ANFREGLNVL   QYFISTHGAR   KGLADTALKT   ANSGYLTRRL   800
801   VDVAQDLVVT   EDDCGTHEGI   MMTPVIEGGD   VKEPLRDRVL   GRVTAEDVLK   850
851   PGTADILVPR   NTLLHEQWCD   LLEENSVDAV   KVRSVVSCDT   DFGVCAHCYG   900
901   RDLARGHIIN   KGEAIGVIAA   QSIGEPGTQL   TMRTFHIGGA   ASRAAAESSI   950
951   QVKNKGSIKL   SNVKSVVNSS   GKLVITSRNT   ELKLIDEFGR   TKESYKVPYG   1000
1001   AVLAKGDGEQ   VAGGETVANW   DPHTMPVITE   VSGFVRFTDM   IDGQTITRQT   1050
1051   DELTGLSSLV   VLDSAERTAG   GKDLRPALKI   VDAQGNDVLI   PGTDMPAQYF   1100
1101   LPGKAIVQLE   DGVQISSGDT   LARIPQESGG   TKDITGGLPR   VADLFEARRP   1150
1151   KEPAILAEIS   GIVSFGKETK   GKRRLVITPV   DGSDPYEEMI   PKWRQLNVFE   1200
1201   GERVERGDVI   SDGPEAPHDI   LRLRGVHAVT   RYIVNEVQDV   YRLQGVKIND   1250
1251   KHIEVIVRQM   LRKATIVNAG   SSDFLEGEQV   EYSRVKIANR   ELEANGKVGA   1300
1301   TYSRDLLGIT   KASLATESFI   SAASFQETTR   VLTEAAVAGK   RDELRGLKEN   1350
1351   VIVGRLIPAG   TGYAYHQDRM   RRRAAGEAPA   APQVTAEDAS   ASLAELLNAG   1400
1401   LGGSDNE           1450

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.