PDB ID 1IW7     CHAIN D
Protein name RNA polymerase beta subunit
PDB 1IW7
The number of similar proteins 84
The number of binding states 10
The number of binding partners 8

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1IW7 (CHAIN: D)
1 Q5SKW1   Q8RQE7   Q8RQE9   Q5SHR6   Q5SHR6  
2 Q8RQE7   Q8RQE9   Q5SHR6  
3 Q9KWU6   Q9EVV4   Q9KWU7  
4 Q9EZJ8   Q9EVV4   Q9KWU7  
5 4239959   1SMY   Q8RQE9   Q9Z9H6  
6 Q8RQE7   Q8RQE9   Q5SHR6   Q5SJG6  
7 Q8RQE7   Q8RQE9   Q5SHR6   Q5SHR6  
8 Q8RQE7   Q8RQE9   Q5SHR6   Q5SHR6   4WQT  
9 Q9KWU6   Q9EVV4   Q9KWU7   Q9KWU8   Q9KWU8  
10 Q5SKW1   Q8RQE7   Q8RQE9   Q5SHR6   Q5SHR6   A7XXA7   A7XX65  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MKKEVRKVRI   ALASPEKIRS   WSYGEVEKPE   TINYRTLKPE   RDGLFDERIF   50
51   GPIKDYECAC   GKYKRQRFEG   KVCERCGVEV   TKSIVRRYRM   GHIELATPAA   100
101   HIWFVKDVPS   KIGTLLDLSA   TELEQVLYFS   KYIVLDPKGA   ILNGVPVEKR   150
151   QLLTDEEYRE   LRYGKQETYP   LPPGVDALVK   DGEEVVKGQE   LAPGVVSRLD   200
201   GVALYRFPRR   VRVEYVKKER   AGLRLPLAAW   VEKEAYKPGE   ILAELPEPYL   250
251   FRAEEEGVVE   LKELEEGAFL   VLRREDEPVA   TYFLPVGMTP   LVVHGEIVEK   300
301   GQPLAEAKGL   LRMPRQVRAA   QVEAEEEGET   VYLTLFLEWT   EPKDYRVQPH   350
351   MNVVVPEGAR   VEAGDKIVAA   IDPEEEVIAE   AEGVVHLHEP   ASILVVKARV   400
401   YPFEDDVEVS   TGDRVAPGDV   LADGGKVKSD   VYGRVEVDLV   RNVVRVVESY   450
451   DIDARMGAEA   IQQLLKELDL   EALEKELLEE   MKHPSRARRA   KARKRLEVVR   500
501   AFLDSGNRPE   WMILEAVPVL   PPDLRPMVQV   DGGRFATSDL   NDLYRRLINR   550
551   NNRLKKLLAQ   GAPEIIIRNE   KRMLQEAVDA   LLDNGRRGAP   VTNPGSDRPL   600
601   RSLTDILSGK   QGRFRQNLLG   KRVDYSGRSV   IVVGPQLKLH   QCGLPKRMAL   650
651   ELFKPFLLKK   MEEKGIAPNV   KAARRMLERQ   RDIKDEVWDA   LEEVIHGKVV   700
701   LLNRAPTLHR   LGIQAFQPVL   VEGQSIQLHP   LVCEAFNADF   DGDQMAVHVP   750
751   LSSFAQAEAR   IQMLSAHNLL   SPASGEPLAK   PSRDIILGLY   YITQVRKEKK   800
801   GAGLEFATPE   EALAAHERGE   VALNAPIKVA   GRETSVGRLK   YVFANPDEAL   850
851   LAVAHGIVDL   QDVVTVRYMG   KRLETSPGRI   LFARIVAEAV   EDEKVAWELI   900
901   QLDVPQEKNS   LKDLVYQAFL   RLGMEKTARL   LDALKYYGFT   FSTTSGITIG   950
951   IDDAVIPEEK   KQYLEEADRK   LLQIEQAYEM   GFLTDRERYD   QILQLWTETT   1000
1001   EKVTQAVFKN   FEENYPFNPL   YVMAQSGARG   NPQQIRQLCG   LRGLMQKPSG   1050
1051   ETFEVPVRSS   FREGLTVLEY   FISSHGARKG   GADTALRTAD   SGYLTRKLVD   1100
1101   VTHEIVVREA   DCGTTNYISV   PLFQPDEVTR   SLRLRKRADI   EAGLYGRVLA   1150
1151   REVEVLGVRL   EEGRYLSMDD   VHLLIKAAEA   GEIQEVPVRS   PLTCQTRYGV   1200
1201   CQKCYGYDLS   MARPVSIGEA   VGIVAAQSIG   EPGTQLTMRT   FHTGGVAGAA   1250
1251   DITQGLPRVI   ELFEARRPKA   KAVISEIDGV   VRIEETEEKL   SVFVESEGFS   1300
1301   KEYKLPKEAR   LLVKDGDYVE   AGQPLTRGAI   DPHQLLEAKG   PEAVERYLVE   1350
1351   EIQKVYRAQG   VKLHDKHIEI   VVRQMMKYVE   VTDPGDSRLL   EGQVLEKWDV   1400
1401   EALNERLIAE   GKTPVAWKPL   LMGVTKSALS   TKSWLSAASF   QNTTHVLTEA   1450
1451   AIAGKKDELI   GLKENVILGR   LIPAGTGSDF   VRFTQVVDQK   TLKAIEEARK   1500
1501   EAVEAKERPA   ARRGVKREQP   GKQA       1550

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.