| PDB ID | 1BMF
|
CHAIN | D |
|---|---|---|---|
| Protein name | BOVINE MITOCHONDRIAL F1-ATPASE | ||
| Uniprot Accession | P00829 | ||
| The number of similar proteins | 89 | ||
| The number of binding states | 9 | ||
| The number of binding partners | 7 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1BMF (CHAIN: D) | |
| 1 |
P00829
P05631
P19483
P19483
|
| 2 | Monomeric state |
| 3 |
P35435
P15999
|
| 4 |
P05631
P19483
P19483
|
| 5 |
P01096
P05631
P19483
P19483
|
| 6 |
P05631
P19483
P19483
P13621
|
| 7 |
P00829
P05631
P19483
P19483
P13621
|
| 8 |
P01096
P01096
P05631
P19483
P19483
|
| 9 |
P00829
P05631
P19483
P19483
P02721
P13620
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 12_ARG | HIS |
gnomAD chr12:57039080 rs41291993 |
- | 0.0210244 | - | - | |
| 12_ARG | HIS |
8.3kJPN chr12:57039080 rs41291993 |
- | 0.1018 | - | - | |
| 26_ASP | VAL |
gnomAD chr12:57039038 rs114920447 |
- | 0.000103392 | - | - | |
| 40_GLY | CYS |
8.3kJPN chr12:57038997 - |
- | 0.0001 | - | - | |
| 102_ILE | SER |
8.3kJPN chr12:57038595 - |
- | 0.0001 | - | - | |
| 115_PRO | ARG |
8.3kJPN chr12:57037734 rs778645597 |
- | 0.0001 | - | - | |
| 123_PHE | LEU |
8.3kJPN chr12:57037709 - |
- | 0.0003 | - | - | |
| 201_ILE | THR |
gnomAD chr12:57037227 rs138308594 |
- | 0.000258488 | - | - | |
| 207_ASN | SER |
gnomAD chr12:57037209 rs142007312 |
- | 0.00248602 | - | - | |
| 233_ALA | PRO |
8.3kJPN chr12:57036561 - |
- | 0.0001 | - | - | |
| 235_THR | ILE |
8.3kJPN chr12:57036554 rs780433436 |
- | 0.0001 | - | - | |
| 285_LEU | PRO |
ClinVar chr12:57036312 - |
Pathogenic | - | - | Hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2|Hypermetabolism due to Defect in Mitochondrial Coupling [MONDO:MONDO:0859302,MedGen:C5774237,OMIM:620085|] | |
| 308_GLN | ARG |
8.3kJPN chr12:57036243 - |
- | 0.0001 | - | - | |
| 310_ILE | VAL |
gnomAD chr12:57033973 rs372401715 |
- | 0.000147307 | - | - | |
| 310_ILE | VAL |
8.3kJPN chr12:57033973 rs372401715 |
- | 0.0002 | - | - | |
| 362_ILE | MET |
8.3kJPN chr12:57033815 - |
- | 0.0001 | - | - | |
| 382_LYS | ARG |
8.3kJPN chr12:57033084 rs745377010 |
- | 0.0002 | - | - | |
| 398_GLU | ASP |
8.3kJPN chr12:57033035 rs888471798 |
- | 0.0003 | - | - | |
| 443_GLN | HIS |
gnomAD chr12:57032900 rs145015204 |
- | 0.000604595 | - | - |