PDB ID 1BMF     CHAIN D
Protein name BOVINE MITOCHONDRIAL F1-ATPASE
Uniprot Accession P00829
The number of similar proteins 89
The number of binding states 9
The number of binding partners 7

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1BMF (CHAIN: D)
1 P00829   P05631   P19483   P19483  
2 Monomeric state
3 P35435   P15999  
4 P05631   P19483   P19483  
5 P01096   P05631   P19483   P19483  
6 P05631   P19483   P19483   P13621  
7 P00829   P05631   P19483   P19483   P13621  
8 P01096   P01096   P05631   P19483   P19483  
9 P00829   P05631   P19483   P19483   P02721   P13620  

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Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   AAQASPSPKA   GATTGRIVAV   IGAVVDVQFD   EGLPPILNAL   EVQGRETRLV   50
51   LEVAQHLGES   TVRTIAMDGT   EGLVRGQKVL   DSGAPIRIPV   GPETLGRIMN   100
101   VIGEPIDERG   PIKTKQFAAI   HAEAPEFVEM   SVEQEILVTG   IKVVDLLAPY   150
151   AKGGKIGLFG   GAGVGKTVLI   MELINNVAKA   HGGYSVFAGV   GERTREGNDL   200
201   YHEMIESGVI   NLKDATSKVA   LVYGQMNEPP   GARARVALTG   LTVAEYFRDQ   250
251   EGQDVLLFID   NIFRFTQAGS   EVSALLGRIP   SAVGYQPTLA   TDMGTMQERI   300
301   TTTKKGSITS   VQAIYVPADD   LTDPAPATTF   AHLDATTVLS   RAIAELGIYP   350
351   AVDPLDSTSR   IMDPNIVGSE   HYDVARGVQK   ILQDYKSLQD   IIAILGMDEL   400
401   SEEDKLTVSR   ARKIQRFLSQ   PFQVAEVFTG   HLGKLVPLKE   TIKGFQQILA   450
451   GEYDHLPEQA   FYMVGPIEEA   VAKADKLAEE   HS     500

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
12_ARG HIS gnomAD
chr12:57039080 		rs41291993
- 0.0210244 -
12_ARG HIS 8.3kJPN
chr12:57039080 		rs41291993
- 0.1018 -
26_ASP VAL gnomAD
chr12:57039038 		rs114920447
- 0.000103392 -
40_GLY CYS 8.3kJPN
chr12:57038997 		-
- 0.0001 -
102_ILE SER 8.3kJPN
chr12:57038595 		-
- 0.0001 -
115_PRO ARG 8.3kJPN
chr12:57037734 		rs778645597
- 0.0001 -
123_PHE LEU 8.3kJPN
chr12:57037709 		-
- 0.0003 -
201_ILE THR gnomAD
chr12:57037227 		rs138308594
- 0.000258488 -
207_ASN SER gnomAD
chr12:57037209 		rs142007312
- 0.00248602 -
233_ALA PRO 8.3kJPN
chr12:57036561 		-
- 0.0001 -
235_THR ILE 8.3kJPN
chr12:57036554 		rs780433436
- 0.0001 -
285_LEU PRO ClinVar
chr12:57036312 		-
Pathogenic - Hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2|Hypermetabolism due to Defect in Mitochondrial Coupling [MONDO:MONDO:0859302,MedGen:C5774237,OMIM:620085|]
308_GLN ARG 8.3kJPN
chr12:57036243 		-
- 0.0001 -
310_ILE VAL gnomAD
chr12:57033973 		rs372401715
- 0.000147307 -
310_ILE VAL 8.3kJPN
chr12:57033973 		rs372401715
- 0.0002 -
362_ILE MET 8.3kJPN
chr12:57033815 		-
- 0.0001 -
382_LYS ARG 8.3kJPN
chr12:57033084 		rs745377010
- 0.0002 -
398_GLU ASP 8.3kJPN
chr12:57033035 		rs888471798
- 0.0003 -
443_GLN HIS gnomAD
chr12:57032900 		rs145015204
- 0.000604595 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.