| PDB ID | 7CCC
|
CHAIN | C |
|---|---|---|---|
| Protein name | F-actin-capping protein subunit alpha | ||
| Uniprot Accession | Q5RKN9 | ||
| The number of similar proteins | 20 | ||
| The number of binding states | 6 | ||
| The number of binding partners | 7 | ||
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 7CCC (CHAIN: C) | |
| 1 |
P68135
P68135
Q923G3
Q12792
|
| 2 |
P14315
|
| 3 |
P14315
Q6EDY6
|
| 4 |
P14315
Q6EDY6
|
| 5 |
P14315
Q91YR1
|
| 6 |
P14315
P58546
|
|
Only interaction residues |
|
||||||||||||||||
|
|
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 10_ASP | ASN |
gnomAD chr1:113162494 rs41283062 |
- | 0.0122157 | - | - | |
| 12_GLU | LYS |
gnomAD chr1:113162500 rs149653791 |
- | 0.00192834 | - | - | |
| 18_ALA | THR |
gnomAD chr7:116528193 rs201789411 |
- | 0.000299664 | - | - | |
| 44_ASN | SER |
gnomAD chr1:113192067 rs76726860 |
- | 0.000286821 | - | - | |
| 81_ASP | ASN |
gnomAD chr7:116544252 rs370326853 |
- | 0.000497754 | - | - | |
| 92_ASN | LYS |
gnomAD chr1:113197143 rs371346893 |
- | 0.000406151 | - | - | |
| 94_ILE | MET |
gnomAD chr7:116544293 rs144500777 |
- | 0.000202893 | - | - | |
| 112_GLU | LYS |
gnomAD chr1:113197201 rs201525157 |
- | 0.000263145 | - | - | |
| 135_HIS | TYR |
gnomAD chr1:113197270 rs201509858 |
- | 0.000264247 | - | - | |
| 154_ILE | THR |
gnomAD chr1:113201678 rs552715621 |
- | 0.000139359 | - | - | |
| 181_ILE | VAL |
gnomAD chr7:116550321 rs141641730 |
- | 0.000417907 | - | - | |
| 211_ASP | GLU |
gnomAD chr1:113209743 rs199731043 |
- | 0.00013179 | - | - | |
| 215_SER | CYS |
gnomAD chr7:116552181 rs140848019 |
- | 0.000657334 | - | - | |
| 226_LYS | ARG |
gnomAD chr1:113212184 rs147970114 |
- | 0.000155925 | - | - |