| PDB ID | 3ZNI
|
CHAIN | C |
|---|---|---|---|
| Protein name | UBIQUITIN-CONJUGATING ENZYME E2 D2 | ||
| Uniprot Accession | P62837 | ||
| The number of similar proteins | 68 | ||
| The number of binding states | 30 | ||
| The number of binding partners | 19 | ||
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 3ZNI (CHAIN: C) | |
| 1 |
P0CG48
Q13191
|
| 2 | Monomeric state |
| 3 |
Q9DAG9
|
| 4 |
O43567
|
| 5 |
P62988
|
| 6 |
Q5X159
|
| 7 |
Q969V5
|
| 8 |
P22681
|
| 9 |
P22681
|
| 10 |
Q96BH1
|
| 11 |
Q96EQ8
|
| 12 |
Q6RCR3
|
| 13 |
Q99496
|
| 14 |
Q7ZTZ6
|
| 15 |
P0CG47
P36406
|
| 16 |
P0CG47
Q00987
|
| 17 |
P0CG48
Q9H0F5
|
| 18 |
P0CG47
Q96EP0
|
| 19 |
P0CG48
Q96FW1
|
| 20 |
P0CG48
Q96CA5
|
| 21 |
P0CG48
P0CG48
|
| 22 |
P62988
Q96PU5
|
| 23 |
P61077
Q9C040
|
| 24 |
P61077
P0CG48
|
| 25 |
P0CG48
Q99PZ6
|
| 26 |
P0CG48
O75592
|
| 27 |
P62837
J3QTR3
Q7YRZ8
|
| 28 |
P0CG47
P0CG47
Q13490
|
| 29 |
P0CG48
P0CG48
Q9H0F5
|
| 30 |
P62837
J3QTR3
Q7YRZ8
Q7YRZ8
|
|
Only interaction residues |
|
||||||||||||||||||||||
|
|
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 4_LYS | ARG |
8.3kJPN chr4:103789885 rs763563358 |
- | 0.0001 | 0.1086 | - | |
| 15_ARG | TRP |
8.3kJPN chr5:138979975 - |
- | 0.0001 | 0.8177 | - | |
| 15_ARG | CYS |
8.3kJPN chr10:60121116 rs769541649 |
- | 0.0001 | 0.6468 | - | |
| 26_VAL | LEU |
8.3kJPN chr7:43978081 - |
- | 0.0001 | 0.4527 | - | |
| 27_GLY | SER |
gnomAD chr7:43978084 rs61751727 |
- | 0.0211142 | 0.225 | - | |
| 29_ASP | ASN |
8.3kJPN chr10:60121158 - |
- | 0.0001 | 0.5581 | - | |
| 34_GLN | LYS |
gnomAD chr10:60121266 rs201319430 |
- | 0.00484562 | 0.6512 | - | |
| 38_MET | THR |
gnomAD chr7:43982449 rs545471592 |
- | 0.000115332 | 0.474 | - | |
| 73_ILE | MET |
8.3kJPN chr7:43988251 rs752952683 |
- | 0.0001 | 0.7026 | - | |
| 81_ASN | SER |
8.3kJPN chr7:43988274 rs745714915 |
- | 0.0001 | 0.179 | - | |
| 140_GLU | ASP |
8.3kJPN chr7:43992270 - |
- | 0.0001 | 0.1618 | - | |
| 146_ALA | THR |
gnomAD chr4:103720097 rs147920467 |
- | 0.0016937 | 0.9462 | - | |
| 146_ALA | SER |
8.3kJPN chr7:43992286 rs1417356646 |
- | 0.0005 | 0.5177 | - |