PDB ID 2G48     CHAIN C
Protein name Islet amyloid polypeptide
Uniprot Accession P10997
The number of similar proteins 8
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2G48 (CHAIN: C)
1 P14735  
2 Monomeric state
3 9CC5  
4 9NZH  
5 5K5G   5K5G  

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Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   KCNTATCATQ   RLANFLVHSS   NNFGAILSST   NVGSNTY     50

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
11_ARG CYS 8.3kJPN
chr12:21531220
rs763676184
- 0.0004 0.1887 -
15_PHE SER 8.3kJPN
chr12:21531233
-
- 0.0001 0.5703 -
20_SER GLY VAR_012080
rs1800203
LB/B - 0.0699 -
20_SER GLY gnomAD
chr12:21531247
rs1800203
- 0.000799472 0.0699 -
20_SER GLY 8.3kJPN
chr12:21531247
rs1800203
- 0.0053 0.0699 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.