PDB ID 1HQM     CHAIN C
Protein name DNA-directed RNA polymerase subunit beta
Uniprot Accession Q9KWU7
The number of similar proteins 85
The number of binding states 10
The number of binding partners 9

Molecule viewer


Only interaction residues
#binding
partners
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MKIKRFGRIR   EVIPLPPLTE   IQVESYKKAL   QADVPPEKRE   NVGIQAAFKE   50
51   TFPIEEGDKG   KGGLVLDFLE   YRIGDPPFSQ   DECREKDLTY   QAPLYARLQL   100
101   IHKDTGLIKE   DEVFLGHLPL   MTEDGSFIIN   GADRVIVSQI   HRSPGVYFTP   150
151   DPARPGRYIA   SIIPLPKRGP   WIDLEVEASG   VVTMKVNKRK   FPLVLLLRVL   200
201   GYDQETLVRE   LSAYGDLVQG   LLDEAVLAMR   PEEAMVRLFT   LLRPGDPPKK   250
251   DKALAYLFGL   LADPKRYDLG   EAGRYKAEEK   LGVGLSGRTL   VRFEDGEFKD   300
301   EVFLPTLRYL   FALTAGVPGH   EVDDIDHLGN   RRIRTVGELM   ADQFRVGLAR   350
351   LARGVRERMV   MGSPDTLTPA   KLVNSRPLEA   ALREFFSRSQ   LSQFKDETNP   400
401   LSSLRHKRRI   SALGPGGLTR   ERAGFDVRDV   HRTHYGRICP   VETPEGANIG   450
451   LITSLAAYAR   VDALGFIRTP   YRRVKNGVVT   EEVVYMTASE   EDRYTIAQAN   500
501   TPLEGDRIAT   DRVVARRRGE   PVIVAPEEVE   FMDVSPKQVF   SLNTNLIPFL   550
551   EHDDANRALM   GSNMQTQAVP   LIRAQAPVVM   TGLEERVVRD   SLAALYAEED   600
601   GEVVKVDGTR   IAVRYEDGRL   VEHPLRRYAR   SNQGTAFDQR   PRVRVGQRVK   650
651   KGDLLADGPA   SEEGFLALGQ   NVLVAIMPFD   GYNFEDAIVI   SEELLKRDFY   700
701   TSIHIERYEI   EARDTKLGPE   RITRDIPHLS   EAALRDLDEE   GIVRIGAEVK   750
751   PGDILVGRTS   FKGEQEPSPE   ERLLRSIFGE   KARDVKDTSL   RVPPGEGGIV   800
801   VGRLRLRRGD   PGVELKPGVR   EVVRVFVAQK   RKLQVGDKLA   NRHGNKGVVA   850
851   KILPVEDMPH   LPDGTPVDVI   LNPLGVPSRM   NLGQILETHL   GLAGYFLGQR   900
901   YISPVFDGAT   EPEIKELLAE   AFNLYFGKRQ   GEGFGVDKRE   KEVLARAEKL   950
951   GLVSPGKSPE   EQLKELFDLG   KVVLYDGRTG   EPFEGPIVVG   QMFIMKLYHM   1000
1001   VEDKMHARST   GPYSLITQQP   LGGKAQFGGQ   RFGEMEVWAL   EAYGAAHTLQ   1050
1051   EMLTIKSDDI   EGRNAAYQAI   IKGEDVPEPS   VPESFRVLVK   ELQALALDVQ   1100
1101   TLDEKDNPVD   IFEGLASKR         1150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.