| PDB ID | 1AHW
|
CHAIN | C |
|---|---|---|---|
| Protein name | TISSUE FACTOR | ||
| Uniprot Accession | P13726 | ||
| The number of similar proteins | 43 | ||
| The number of binding states | 5 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1AHW (CHAIN: C) | |
| 1 |
S49220
P01837
|
| 2 | Monomeric state |
| 3 |
1JPS
1JPS
|
| 4 |
P08709
P08709
|
| 5 |
S49220
P01837
P01837
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 4_THR | ALA |
VAR_014298
rs3917604 |
LB/B | - | 0.0646 | - | |
| 4_THR | ALA |
gnomAD chr1:95005919 rs3917604 |
- | 0.00180172 | 0.0646 | - | |
| 8_ALA | THR |
gnomAD chr1:95005907 rs148395733 |
- | 0.000298567 | 0.0895 | - | |
| 22_ILE | VAL |
gnomAD chr1:95005865 rs114064069 |
- | 0.000799529 | 0.1671 | - | |
| 61_ASP | GLY |
gnomAD chr1:95001655 rs143237190 |
- | 0.00152691 | 0.3446 | - | |
| 77_SER | PHE |
8.3kJPN chr1:95001607 rs924494158 |
- | 0.0004 | 0.5556 | - | |
| 113_ILE | VAL |
VAR_014299
rs3917627 |
LB/B | - | 0.1624 | - | |
| 117_GLU | GLY |
8.3kJPN chr1:94998791 - |
- | 0.0001 | 0.1998 | - | |
| 131_ARG | TRP |
VAR_012008
rs5901 |
LB/B | - | 0.1717 | - | |
| 131_ARG | TRP |
gnomAD chr1:94998750 rs5901 |
- | 0.00197181 | 0.1717 | - | |
| 131_ARG | TRP |
8.3kJPN chr1:94998750 rs5901 |
- | 0.0076 | 0.1717 | - | |
| 134_VAL | LEU |
8.3kJPN chr1:94998741 - |
- | 0.0001 | 0.3036 | - | |
| 142_SER | ARG |
gnomAD chr1:94998715 rs200192517 |
- | 0.000183242 | 0.5562 | - | |
| 167_THR | ARG |
8.3kJPN chr1:94998032 - |
- | 0.0001 | 0.1452 | - | |
| 196_ARG | GLN |
8.3kJPN chr1:94997945 rs780707936 |
- | 0.0001 | 0.5284 | - | |
| 197_THR | ALA |
8.3kJPN chr1:94997943 - |
- | 0.0001 | 0.0804 | - | |
| 200_ARG | TRP |
gnomAD chr1:94997934 rs143207556 |
- | 0.000127248 | 0.2344 | - | |
| 205_SER | GLY |
8.3kJPN chr1:94997919 rs200768220 |
- | 0.0003 | 0.4172 | - |