PDB ID 1AHW     CHAIN C
Protein name TISSUE FACTOR
Uniprot Accession P13726
The number of similar proteins 43
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1AHW (CHAIN: C)
1 S49220   P01837  
2 Monomeric state
3 1JPS   1JPS  
4 P08709   P08709  
5 S49220   P01837   P01837  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   SGTTNTVAAY   NLTWKSTNFK   TILEWEPKPV   NQVYTVQIST   KSGDWKSKCF   50
51   YTTDTECDLT   DEIVKDVKQT   YLARVFSYPA   GNVESTGSAG   EPLYENSPEF   100
101   TPYLETNLGQ   PTIQSFEQVG   TKVNVTVEDE   RTLVRRNNTF   LSLRDVFGKD   150
151   LIYTLYYWKS   SSSGKKTAKT   NTNEFLIDVD   KGENYCFSVQ   AVIPSRTVNR   200
201   KSTDSPVECM   GQEKGEFRE         250

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
4_THR ALA VAR_014298 rs3917604
LB/B - -
4_THR ALA gnomAD
chr1:95005919
rs3917604
- 0.00180172 -
8_ALA THR gnomAD
chr1:95005907
rs148395733
- 0.000298567 -
22_ILE VAL gnomAD
chr1:95005865
rs114064069
- 0.000799529 -
61_ASP GLY gnomAD
chr1:95001655
rs143237190
- 0.00152691 -
77_SER PHE 8.3kJPN
chr1:95001607
rs924494158
- 0.0004 -
113_ILE VAL VAR_014299 rs3917627
LB/B - -
117_GLU GLY 8.3kJPN
chr1:94998791
-
- 0.0001 -
131_ARG TRP VAR_012008 rs5901
LB/B - -
131_ARG TRP gnomAD
chr1:94998750
rs5901
- 0.00197181 -
131_ARG TRP 8.3kJPN
chr1:94998750
rs5901
- 0.0076 -
134_VAL LEU 8.3kJPN
chr1:94998741
-
- 0.0001 -
142_SER ARG gnomAD
chr1:94998715
rs200192517
- 0.000183242 -
167_THR ARG 8.3kJPN
chr1:94998032
-
- 0.0001 -
196_ARG GLN 8.3kJPN
chr1:94997945
rs780707936
- 0.0001 -
197_THR ALA 8.3kJPN
chr1:94997943
-
- 0.0001 -
200_ARG TRP gnomAD
chr1:94997934
rs143207556
- 0.000127248 -
205_SER GLY 8.3kJPN
chr1:94997919
rs200768220
- 0.0003 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.