PDB ID 7WNM     CHAIN B
Protein name Angiotensin-converting enzyme 2
Uniprot Accession Q9BYF1
The number of similar proteins 70
The number of binding states 6
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
7WNM (CHAIN: B)
1 P0DTC2  
2 Monomeric state
3 Q9BYF1  
4 7E7E   7E7E  
5 Q9BYF1   Q6Q1S2  
6 Q56NL1   P59594  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   MSSSSWLLLS   LVAVTAAQST   IEEQAKFFLD   KFNHEAEDLF   YQSSLASWNY   50
51   NTNITEENVQ   NMNNAGDKWS   AFLKEQSTLA   QMYPLQEIQN   LTVKLQLQAL   100
101   QQNGSSVLSE   DKSKRLNTIL   NTMSTIYSTG   KVCNPDNPQE   CLLLEPGLNE   150
151   IMANSLDYNE   RLWAWESWRS   EVGKQLRPLY   EEYVVLKNEM   ARANHYEDYG   200
201   DYWRGDYEVN   GVDGYDYSRG   QLIEDVEHTF   EEIKPLYEHL   HAYVRAKLMN   250
251   AYPSYISPIG   CLPAHLLGDM   WGQFWTNLYS   LTVPFGQKPN   IDVTDAMVDQ   300
301   AWDAQRIFKE   AEKFFVSVGL   PNMTQGFWEN   SMLTDPGNVQ   KAVCHPTAWD   350
351   LGKGDFRILM   CTKVTMDDFL   TAHHEMGHIQ   YDMAYAAQPF   LLRNGANEGF   400
401   HEAVGEIMSL   SAATPKHLKS   IGLLSPDFQE   DNETEINFLL   KQALTIVGTL   450
451   PFTYMLEKWR   WMVFKGEIPK   DQWMKKWWEM   KREIVGVVEP   VPHDETYCDP   500
501   ASLFHVSNDY   SFIRYYTRTL   YQFQFQEALC   QAAKHEGPLH   KCDISNSTEA   550
551   GQKLFNMLRL   GKSEPWTLAL   ENVVGAKNMN   VRPLLNYFEP   LFTWLKDQNK   600
601   NSFVGWSTDW   SPYADQSIKV   RISLKSALGD   KAYEWNDNEM   YLFRSSVAYA   650
651   MRQYFLKVKN   QMILFGEEDV   RVANLKPRIS   FNFFVTAPKN   VSDIIPRTEV   700
701   EKAIRMSRSR   INDAFRLNDN   SLEFLGIQPT   LGPPNQPPVS     750

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
26_LYS ARG VAR_023082
rs4646116
LB/B - 0.0765 -
468_ILE VAL VAR_083726
-
LB/B - 0.1962 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.