| PDB ID | 5HZP
|
CHAIN | B |
|---|---|---|---|
| Protein name | C4b-binding protein alpha chain | ||
| Uniprot Accession | P04003 | ||
| The number of similar proteins | 8 | ||
| The number of binding states | 5 | ||
| The number of binding partners | 3 | ||
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 5HZP (CHAIN: B) | |
| 1 |
P16947
P16947
|
| 2 | Monomeric state |
| 3 |
P50468
|
| 4 |
W0T1Y4
|
| 5 |
Q54901
Q54901
|
|
Only interaction residues |
|
||||||||||
|
|
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 12_ALA | VAL |
VAR_048815
rs17020956 |
LB/B | - | 0.0876 | - | |
| 12_ALA | VAL |
gnomAD chr1:207287481 rs17020956 |
- | 0.00678686 | 0.0876 | - | |
| 61_ILE | MET |
8.3kJPN chr1:207287629 - |
- | 0.0001 | 0.1014 | - | |
| 78_ILE | VAL |
8.3kJPN chr1:207288808 - |
- | 0.0001 | 0.1022 | - |