| PDB ID | 4QRS
|
CHAIN | B |
|---|---|---|---|
| Protein name | Beta-2-microglobulin | ||
| Uniprot Accession | P61769 | ||
| The number of similar proteins | 1150 | ||
| The number of binding states | 28 | ||
| The number of binding partners | 17 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 4QRS (CHAIN: B) | |
| 1 |
P30460
|
| 2 | Monomeric state |
| 3 |
P15813
|
| 4 |
P55899
|
| 5 |
P61769
|
| 6 |
Q5GL29
|
| 7 |
4KDT
|
| 8 |
5WHK
P55899
|
| 9 |
P55899
7Q15
|
| 10 |
P30504
P30504
|
| 11 |
P17693
Q8N423
|
| 12 |
P01892
P68979
|
| 13 |
P01901
Q8QMP2
|
| 14 |
P01900
5WER
|
| 15 |
F6IQY1
6ID4
|
| 16 |
P15813
6V7Z
|
| 17 |
Q95460
P01732
|
| 18 |
Q8NHL6
Q4A1U8
|
| 19 |
P55899
P02768
|
| 20 |
6FGB
P55899
|
| 21 |
P01861
P55899
|
| 22 |
P06126
A0A1B0GX56
|
| 23 |
P61769
P61769
|
| 24 |
U5YKE0
6W51
6W51
|
| 25 |
P05534
P01732
P01732
|
| 26 |
A0A5B8RNS7
6UZ1
6UZ1
|
| 27 |
P01857
P55899
P02768
|
| 28 |
P61769
P61769
P61769
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 33_SER | PRO |
8.3kJPN chr15:45007710 - |
- | 0.0001 | 0.1026 | - | |
| 44_GLU | ASP |
8.3kJPN chr15:45007745 - |
- | 0.0001 | 0.1886 | - | |
| 76_ASP | ASN |
VAR_076691
rs398122820 |
LP/P | - | 0.4906 | Amyloidosis 8 (AMYL8) [MIM:105200] | |
| 76_ASP | ASN |
ClinVar chr15:45007839 rs398122820 |
Pathogenic | - | 0.4906 | Familial visceral amyloidosis, Ostertag type|Non-Hodgkin lymphoma [MONDO:MONDO:0007099,MedGen:C0268389,OMIM:105200,Orphanet:85450|Human Phenotype Ontology:HP:0012539,MONDO:MONDO:0018908,MedGen:C0024305,Orphanet:547] |