| PDB ID | 4K71
|
CHAIN | B |
|---|---|---|---|
| Protein name | IgG receptor FcRn large subunit p51 | ||
| Uniprot Accession | P55899 | ||
| The number of similar proteins | 20 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 5 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 4K71 (CHAIN: B) | |
| 1 |
P61769
P02768
|
| 2 | Monomeric state |
| 3 |
P61769
|
| 4 |
7Q15
P61769
|
| 5 |
P61769
6FGB
6FGB
|
| 6 |
P61769
5WHK
5WHK
|
| 7 |
P01857
P61769
P02768
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 14_VAL | GLY |
8.3kJPN chr19:50017175 - |
- | 0.0033 | 0.5461 | - | |
| 20_GLY | ARG |
gnomAD chr19:50017192 rs548622027 |
- | 0.000322671 | 0.4363 | - | |
| 32_PRO | LEU |
8.3kJPN chr19:50017229 rs764132164 |
- | 0.0004 | 0.4015 | - | |
| 42_ARG | GLN |
gnomAD chr19:50017259 rs566716525 |
- | 0.000111776 | 0.1191 | - | |
| 45_ALA | VAL |
8.3kJPN chr19:50017268 rs756120751 |
- | 0.0001 | 0.5845 | - | |
| 48_CYS | TYR |
gnomAD chr19:50017277 rs151255924 |
- | 0.000860069 | 0.2048 | - | |
| 68_LEU | GLN |
8.3kJPN chr19:50017337 - |
- | 0.0001 | 0.8193 | - | |
| 76_LEU | VAL |
8.3kJPN chr19:50017360 - |
- | 0.0001 | 0.1189 | - | |
| 83_GLY | ARG |
8.3kJPN chr19:50017381 rs201043787 |
- | 0.0001 | 0.1568 | - | |
| 105_VAL | LEU |
8.3kJPN chr19:50017524 - |
- | 0.0001 | 0.1089 | - | |
| 109_LYS | ASN |
gnomAD chr19:50017538 rs150420714 |
- | 0.0065323 | 0.5043 | - | |
| 140_ARG | LEU |
8.3kJPN chr19:50017630 - |
- | 0.0002 | 0.0908 | - | |
| 160_PRO | SER |
8.3kJPN chr19:50017689 rs373482955 |
- | 0.0001 | 0.7005 | - | |
| 162_ARG | HIS |
8.3kJPN chr19:50017696 rs200294618 |
- | 0.0001 | 0.4089 | - | |
| 164_ARG | TRP |
gnomAD chr19:50017701 rs145251123 |
- | 0.000189109 | 0.1878 | - | |
| 183_ARG | CYS |
8.3kJPN chr19:50027778 rs779240739 |
- | 0.0001 | 0.5886 | - | |
| 184_LEU | VAL |
gnomAD chr19:50027781 rs141886822 |
- | 0.000196207 | 0.2262 | - | |
| 187_ARG | GLN |
8.3kJPN chr19:50027791 rs747515242 |
- | 0.001 | 0.093 | - | |
| 214_ARG | GLN |
8.3kJPN chr19:50027872 rs147601685 |
- | 0.0037 | 0.1291 | - | |
| 236_ALA | THR |
8.3kJPN chr19:50027937 rs767515922 |
- | 0.0001 | 0.1248 | - | |
| 246_ASP | ASN |
8.3kJPN chr19:50027967 rs573657624 |
- | 0.0002 | 0.2868 | - | |
| 257_ALA | VAL |
8.3kJPN chr19:50028001 rs777748221 |
- | 0.0001 | 0.1277 | - | |
| 258_GLY | VAL |
8.3kJPN chr19:50028004 - |
- | 0.0001 | 0.8432 | - |