PDB ID 3F8U     CHAIN B
Protein name Tapasin
Uniprot Accession O15533
The number of similar proteins 6
The number of binding states 5
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3F8U (CHAIN: B)
1 P30101  
2 Monomeric state
3 P61769   7TUE  
4 P01899   P61769   P30101  
5 7TUF   7TUF   7TUF  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   MKSLSLLLAV   ALGLATAVSA   GPAVIECWFV   EDASGKGLAK   RPGALLLRQG   50
51   PGEPPPRPDL   DPELYLSVHD   PAGALQAAFR   RYPRGAPAPH   CEMSRFVPLP   100
101   ASAKWASGLT   PAQNCPRALD   GAWLMVSISS   PVLSLSSLLR   PQPEPQQEPV   150
151   LITMATVVLT   VLTHTPAPRV   RLGQDALLDL   SFAYMPPTSE   AASSLAPGPP   200
201   PFGLEWRRQH   LGKGHLLLAA   TPGLNGQMPA   AQEGAVAFAA   WDDDEPWGPW   250
251   TGNGTFWLPR   VQPFQEGTYL   ATIHLPYLQG   QVTLELAVYK   PPKVSLMPAT   300
301   LARAAPGEAP   PELLCLVSHF   YPSGGLEVEW   ELRGGPGGRS   QKAEGQRWLS   350
351   ALRHHSDGSV   SLSGHLQPPP   VTTEQHGARY   ACRIHHPSLP   ASGRSAEVTL   400
401   E           450

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
23_GLY ARG 8.3kJPN
chr6:33281552 		-
- 0.0001 -
34_PRO ARG gnomAD
chr6:33281518 		rs139155669
- 0.000225763 -
35_PRO SER 8.3kJPN
chr6:33281516 		rs1306642119
- 0.0007 -
38_PRO SER gnomAD
chr6:33281507 		rs376978188
- 0.000335167 -
39_ASP TYR gnomAD
chr6:33281504 		rs45583737
- 0.0050168 -
49_HIS GLN 8.3kJPN
chr6:33281472 		rs1312830938
- 0.0001 -
73_MET VAL 8.3kJPN
chr6:33281186 		rs768120968
- 0.0001 -
105_MET VAL 8.3kJPN
chr6:33281090 		rs1260365536
- 0.0001 -
123_PRO ALA 8.3kJPN
chr6:33281036 		-
- 0.0001 -
127_GLN HIS 8.3kJPN
chr6:33281022 		-
- 0.0001 -
149_ARG GLN 8.3kJPN
chr6:33273128 		rs768577222
- 0.0001 -
166_PRO THR 8.3kJPN
chr6:33273078 		rs145952108
- 0.0001 -
168_THR ILE gnomAD
chr6:33273071 		rs142455342
- 0.000394401 -
177_PRO LEU gnomAD
chr6:33273044 		rs149606847
- 0.000350061 -
177_PRO LEU 8.3kJPN
chr6:33273044 		rs149606847
- 0.0004 -
178_GLY ASP 8.3kJPN
chr6:33273041 		-
- 0.0002 -
188_ARG HIS gnomAD
chr6:33273011 		rs138273100
- 0.000244203 -
232_GLY ARG 8.3kJPN
chr6:33272880 		rs756406534
- 0.0002 -
240_THR ARG gnomAD
chr6:33272855 		rs2071888
- 0.558856 -
240_THR ARG 8.3kJPN
chr6:33272855 		rs2071888
- 0.3422 -
254_HIS PRO 8.3kJPN
chr6:33272813 		rs201276892
- 0.0023 -
259_GLN TER 8.3kJPN
chr6:33272799 		-
- 0.0001 -
270_LYS GLU 8.3kJPN
chr6:33272766 		rs948233488
- 0.0001 -
273_LYS GLU 8.3kJPN
chr6:33272407 		-
- 0.0001 -
283_ARG GLN 8.3kJPN
chr6:33272376 		rs185298453
- 0.0001 -
287_GLY GLU 8.3kJPN
chr6:33272364 		-
- 0.0001 -
296_LEU PHE gnomAD
chr6:33272338 		rs566153136
- 0.000235284 -
296_LEU PHE 8.3kJPN
chr6:33272338 		rs566153136
- 0.001 -
305_GLY ASP gnomAD
chr6:33272310 		rs200280998
- 0.000114236 -
313_ARG GLN gnomAD
chr6:33272286 		rs11549919
- 0.000199227 -
331_ALA VAL gnomAD
chr6:33272232 		rs200098001
- 0.000315999 -
337_ASP GLU 8.3kJPN
chr6:33272213 		-
- 0.0001 -
363_ARG GLN 8.3kJPN
chr6:33272136 		rs750940622
- 0.0001 -
380_LEU PRO 8.3kJPN
chr6:33272085 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.